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5-Methoxy-L-tryptophan

产品编号:4078644
规格:98-102%
CAS NO:25197-96-0
包装规格:100 MG,250 MG,500 MG,1 G
产品类别:进口试剂
品牌:Sigma-Aldrich
优惠价:立即咨询
产品编号包装单位单价(元)国内现货国外库存询价单
4078644100 MG1930
4078644250 MG3780
4078644500 MG7290
40786441 G12660
产品别名

25197-96-0

5-Methoxy-L-tryptophan

L-2-Amino-3-(5-methoxyindolyl)propionic acid

基本信息
Empirical Formula【经验(实验)分子式】
C12H14N2O3
Molecular weight
234.25
General description【一般描述】
5-Methoxy-L-tryptophan is a L-tryptophan metabolite that exhibits anti-inflammatory and tumor-suppressing activities. 5-Methoxy-L-tryptophan is synthesized by tryptophan hydroxylase (TPH) and hydroxyindole O-methyltransferase (HIOMT). Recent study indicates 5-methoxytryptophan as a biomarker of progression of chronic kidney disease (CKD). Its levels decrease during disease and treatment with 5-methoxytryptophan ameliorates kidney fibrosis n mice model of CKD. 5-Methoxytryptophan appears to inhibit I?B/NF-?B signaling and enhaces Keap1/Nrf2 signaling in mice model of unilateral ureteral obstruction. Literature often uses the name 5-Methoxytryptophan instead L-5-Methoxytryptophan.
产品性质
Quality Level【质量水平】
100
Assay【测定】
98-102%
form【形式】
solid
optical activity【旋光性】
[α]20/D -30 to -28° in water
color【颜色】
off-white to light yellow
storage temp.【储存温度】
2-8℃
安全信息
Pictograms【象形图】
GHS06
Signal word【警示用语:】
Danger
Hazard Statements
H301
Precautionary Statements
P301 + P310 + P330
Hazard Classifications【危险分类】
Acute Tox. 3 Oral
Storage Class Code【储存分类代码】
6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
WGK
WGK 1
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