Anti-Dystrophin antibody, Mouse monoclonal

NA.41

Dystrophin is a rod-shaped cytoskeletal protein located to the periphery (plasma membrane) of normal striated muscle fibers.
Anti-Dystrophin antibody, Mouse monoclonal (mouse IgG2b isotype) is derived from the MANDYS8 hybridoma produced by the fusion of mouse myeloma cells and splenocytes from mouse immunized with fragment of recombinant human dystrophin. Dystrophin is a 427 kD protein which joins the actin cytoskeleton to laminin. It possesses multiple domains and is localized to the extracellular matrix. Dystrophin contains NH2-terminal domain for actin binding. The C-terminal domain interacts with dystrophin associated protein (DAP).

Anti-Dystrophin antibody, Mouse monoclonal specifically recognizes an epitope located on the rod domain of the human dystrophin molecule.

recombinant human dystrophin

Anti-Dystrophin antibody, Mouse monoclonal has been used in immunoblotting and immunohistochemistry.

Dystrophin is known to prevent muscle fibre injury due to contraction.

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide as preservative.

This product is for R&D use only, not for drug, household, or other uses.

200

mouse

purified from hybridoma cell culture

primary antibodies

MANDYS8, monoclonal

buffered aqueous solution

~427 kDa

human, mouse, porcine, rabbit, rat

~1.0 mg/mL

immunoblotting: suitable
immunohistochemistry: 5-10 μg/mL using acetone fixed rat tongue frozen sections

IgG2b

P11532

dry ice

−20℃

12 - Non Combustible Liquids

WGK 3