Microbial DNA standard from Akkermansia muciniphila

NA.24

Standardization of sample analysis is currently needed in microbiome genomics research workflow. Lack of standardization can lead to biases and errors in common processes during sample preparation and analysis such as sample amplification, sequencing and bioinformatics analyses.¹ Akkermansia muciniphila genomic DNA microbial standard can serve as standard for benchmarking the performance along the workflow of microbiomics or meta-genomics analyses and as a tool to increase reproducibility and allow comparison of results obtained by different labs.
Akkermansia muciniphila is a gram negative, anaerobic, non motile, non spore forming and oval shaped bacterium. A. muciniphila inhabits the gastrointestinal tracts of more than 90% of adults and constitutes 1 to 4% of the fecal microbiota.² A. muciniphila level was suggested to be a biomarker for a healthy intestin. ³
A. muciniphila degrades mucus and utilizes it as a carbon/nitrogen source. Consequently, the host produces additional mucus while the bacterium produces oligosaccharides and Short Chain Fatty Acids (SCFAs) that can be utilized by the host and trigger the immune system. An additional protective effect of the SCFA is stimulation of mucus-associated microbiota growth, that serves as a barrier against penetration of pathogens to intestinal cells. ^2,4

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Suitable for Quantitative standard for PCR, Sequencing and NGS

Liquid - The genomic DNA is provided at ≥10 ng/μL concentration in TE buffer pH 8.0

It is recommended to avoid freeze thaw cycles of this product.

liquid

10 ng/μL

PCR: suitable

ambient

−20℃

12 - Non Combustible Liquids

WGK 1