Anti-Chloride Channel-2 (CLC-2, Clcn2) antibody produced in rabbit

MFCD02096079

NA.41

synthetic peptide corresponding to amino acids 888-906 of the rat chloride channel-2 (CLC-2).

Anti-Chloride Channel-2 antibody produced in rabbit is suitable for western blot (chemiluminescent) at a working dilution of 1:200-1:400 using rat membranes and ECL.

The encoded protein, voltage-gated chloride channel, is a transmembrane protein that maintains chloride ion homeostasis in various cells. Defects in this gene may be a cause of certain epilepsies. Autosomal-recessive mutations ion this gene cause a leukoencephalopathy that affects brain ion and water homoeostasis. It is characterized by intramyelinic oedema. It is involved in maintaining the volume of trabecular meshwork cells by adjusting the outflow of aqueous solutions and for maintaining the fluid balance. It may be a potential target for the treatment of primary open angle glaucoma.

Lyophilized at ~0.6 mg/ml from phosphate buffered saline, pH 7.4, containing 1% bovine serum albumin, 5% sucrose and 0.025% sodium azide

rabbit

200

unconjugated

affinity isolated antibody

primary antibodies

polyclonal

lyophilized powder

rat

western blot (chemiluminescent): 1:200-1:400 using rat membranes and ECL

P35525

−20℃

rat ... Clcn2(29232)

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