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白介素1α 人
Interleukin-1α human
| 产品编号： | 4081070 |
| 规格： | IL-1α, recombinant, expressed in E. coli, lyophilized powder, suitable for cell culture |
| 包装规格： | 2 μG，10 μG |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品别名
白介素1α 人
Interleukin-1α human
IL-1α
Lymphocyte activating factor
hIL-1α.
基本信息
| MDL number | MFCD00164814 |
| NACRES | NA.77 |
| Quality【质量】 | endotoxin tested |
| General description【一般描述】 | Interleukin-1α (IL-1α) is a cytokine that belongs to the interleukin-1 (IL-1) family. It is located intracellularly in hematopoietic and non-hematopoietic cells. IL-1α gene is located on the human chromosome at 2q14.1. |
| Application【应用】 | Interleukin-1α (IL-1α) has been used:
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| Biochem/physiol Actions【生化/生理作用】 | Interleukin-1α (IL-1α) plays a crucial role in inflammation during cell necrosis. It also regulates the recruitment of interleukin-1β (IL-1β), neutrophils, chemokines, and other cytokines at the site of injury. IL-1α exhibits a dual function of binding to its cell surface receptor as well as chromatin. |
| Physical form【外形】 | Lyophilized from 0.2 μm filtered 10 mM sodium phosphate , pH 8.0, plus 50 mm NaCl and 50 μg bovine serum albumin (BSA) per μg cytokine. |
| Analysis Note【分析说明】 | The proliferative activity of human IL-1α is tested in culture using the murine cell line D10S. |
产品性质
| Quality Level【质量水平】 | 100 |
| biological source【生物来源】 | human |
| recombinant【重组】 | expressed in E. coli |
| Assay【测定】 | ≥98% (SDS-PAGE and HPLC) |
| form【形式】 | lyophilized powder |
| mol wt【分子量】 | ~17 kDa |
| technique(s) | cell culture | mammalian: suitable |
| UniProt accession no.【UniProt登记号】 | P01583 |
| storage temp.【储存温度】 | −20℃ |
| Gene Information | human ... IL1A(3552) |
| packaging【包装】 | 2 μg in serum bottle |
安全信息
| Pictograms【象形图】 | GHS07 |
| Signal word【警示用语：】 | Warning |
| Hazard Statements | H315 - H319 - H335 |
| Precautionary Statements | P261 - P305 + P351 + P338 |
| Hazard Classifications【危险分类】 | Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3 |
| Target Organs【靶器官】 | Respiratory system |
| Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
| Personal Protective Equipment【个人防护装备】 | dust mask type N95 (US), Eyeshields, Gloves |
