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MultiScreen Permeability Filter Plate, 0.4 μm, non-sterile
| 产品编号： | 4082436 |
| 规格： | This 96-well filter plate has a Polycarbonate membrane used for Permeability studies. |
| 包装规格： | 10 EA |
| 产品类别： | 进口试剂 |
| 品牌： | Millipore |
| 优惠价： | 立即咨询 |
基本信息
| eCl@ss | 32039006 |
| NACRES | NB.22 |
| General description【一般描述】 | Filter Code: PCF Increasing drug candidate predictability earlier in the discovery pipeline using non-cell-based assays can improve candidate throughput during the ADME stage. Non-cell-based permeability assays are predictive models for oral absorption of development candidates. MultiScreen Permeability, MultiScreen-IP, and MultiScreen Acceptor plates support artificial membrane strategies for predicting passive transport. Membranes have uniform pore structure and density for reliable transport: - Individual wells minimize candidate cross-talk - Compatibility with automated liquid handling systems increases throughput Permeability Assay: - The MultiScreen Permeability plate has a polycarbonate membrane, which supports a hexane/hexadecane artificial layer for permeability assays.1 PAMPA Assay: - The MultiScreen-IP plate has a hydrophobic PVDF membrane, which supports a lipid bilayer for PAMPA asays.2,3 MultiScreen Acceptor Plate: - The MultiScreen Acceptor plate can be used with either plate to capture passively transported compounds. Constructed of 100% PTFE, the plate can improve LC/MS results depending on the charge of the small molecules being evaluated. |
| Application【应用】 | Research Category Assays Protein |
| Physical form【外形】 | Color Code: 透明 |
| Other Notes【其他说明】 | Automation Compatible: No |
| Legal Information【法律信息】 | MULTISCREEN is a registered trademark of Merck KGaA, Darmstadt, Germany |
产品性质
| material【物料】 | flat bottom wells polycarbonate membrane polystyrene |
| Quality Level【质量水平】 | 400 |
| sterility【无菌性】 | non-sterile |
| product line【产品线】 | MultiScreen® |
| feature【特点】 | lid |
| manufacturer/tradename | MultiScreen® |
| technique(s) | DNA purification: suitable activity assay: suitable (with precipitations) ligand binding assay: suitable parallel artificial membrane permeation assay (PAMPA): suitable receptor binding assay: suitable |
| plate size【板尺寸】 | 96 wells |
| well maximum volume【孔最大体积】 | 300 μL |
| working volume【工作体积】 | 125 μL |
| pore size【孔径】 | 0.4 μm pore size |
| test parameters【试验参数】 | sample volume: 100 μL (per well) |
| application(s) | sample preparation |
| shipped in【运输】 | ambient |
