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Sumanirole Maleate-CAS 179386-44-8-Calbiochem
产品价格查看更多规格...
| 产品编号 | 包装单位 | 单价(元) | 国内现货 | 国外库存 | 询价单 |
| 4083617 | 5 MG | 2500 |
产品别名
179386-44-8
Sumanirole Maleate-CAS 179386-44-8-Calbiochem
Dopamine D2 receptor Agonist, Sumanirole, PNU 95666, PNU95666
基本信息
| Empirical Formula【经验(实验)分子式】 | C11H13N3O · xC4H4O4 |
| Molecular weight | 203.24 (free base basis) |
| MDL number | MFCD09832637 |
| General description【一般描述】 | An extremely selective dopamine D2 receptor agonist (Ki = 9 nM). Commonly used in Parkinson′s Disease models and to reproduce cocaine′s discriminative stimulus effects. Sumanirole has greater than 200-fold selectivity for the D2 receptor subtype versus the other dopamine receptor subtypes in radioligand binding assays. In cell-based assays, sumanirole is a fully efficacious agonist, with EC50 values between 17 and 75 nM. In animals, sumanirole elicits many physiological responses attributed to D2-like receptor function. |
| Warning【警告】 | Toxicity: Standard Handling (A) |
| Other Notes【其他说明】 | Achat-Mendes, C. et al., 2010. J. Pharmacol. Exp. Ther.334, 556. McCall, R. B. et al., 2005. J. Pharmacol. Exp. Ther.314, 1248. |
| Legal Information【法律信息】 | CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany |
产品性质
| Quality Level【质量水平】 | 100 |
| Assay【测定】 | ≥98% (HPLC) |
| form【形式】 | solid |
| potency【效能】 | 9 nM Ki |
| manufacturer/tradename | Calbiochem® |
| storage condition【储存条件】 | OK to freeze protect from light |
| color【颜色】 | off-white |
| solubility【溶解性】 | DMSO: 16 mg/mL |
| storage temp.【储存温度】 | −20℃ |
安全信息
| Storage Class Code【储存分类代码】 | 11 - Combustible Solids |
| WGK | WGK 3 |
