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Furin Substrate, Fluorogenic-Calbiochem
| 产品编号： | 4083844 |
| 规格： | A fluorogenic substrate for furin, a mammalian homolog of the yeast Kex2 endoprotease (kcat/Km ~ 2 x 104 s-1M-1). |
| 包装规格： | 5 MG |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
基本信息
| Empirical Formula【经验(实验)分子式】 | C37H57N13O9 |
| Molecular weight | 827.93 |
| General description【一般描述】 | A fluorogenic substrate for furin, a mammalian homolog of the yeast Kex2 endoprotease (kcat/Km ~ 2 x 104 s-1M-1). A fluorogenic substrate for furin (kcat/Km ~2 X 104 M-1 s-1), a mammalian homolog of the yeast Kex2 endoprotease. Also serves as a substrate for related protein, prohormone convertase 2 (PC2) (kcat/Km ~6 X 103 M-1 s-1). Excitation max: ~360-380 nm; emission max: ~430-460 nm). |
| Biochem/physiol Actions【生化/生理作用】 | Primary Target Fluorogenic substrate for furin kcat/Km ~ 2 x 104 s-1M-1 for furin Product does not compete with ATP. Reversible: no Cell permeable: no |
| Warning【警告】 | Toxicity: Standard Handling (A) |
| Sequence【序列】 | Pyr-Arg-Thr-Lys-Arg-AMC |
| Physical form【外形】 | Supplied as a trifluoroacetate salt. |
| Reconstitution【重悬】 | Following reconstitution, aliquot and freeze (-20°). Stock solutions are stable for up to 3 months at -20°C. |
| Other Notes【其他说明】 | Lamango, N.S., et al. 1996. Arch. Biochem. Biophys.330, 238. Hatsuzawa, K., et al. 1992. J. Biol. Chem. 267, 16094. |
| Legal Information【法律信息】 | CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany |
产品性质
| Quality Level【质量水平】 | 100 |
| Assay【测定】 | ≥95% (HPLC) |
| form【形式】 | solid |
| manufacturer/tradename | Calbiochem® |
| storage condition【储存条件】 | OK to freeze desiccated (hygroscopic) protect from light |
| color【颜色】 | white |
| solubility【溶解性】 | water: 10 mg/mL DMSO: soluble |
| fluorescence【荧光】 | λex 360 - 380 nm λem 430-460 nm |
| shipped in【运输】 | ambient |
| storage temp.【储存温度】 | −20℃ |
| packaging【包装】 | 5 mg in Plastic ampoule |
安全信息
| Storage Class Code【储存分类代码】 | 11 - Combustible Solids |
| WGK | WGK 1 |
