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Luciferase Inhibitor II-CAS 10205-56-8-Calbiochem
产品编号: | 4083895 |
规格: | The Luciferase Inhibitor II, also referenced under CAS 10205-56-8, controls the biological activity of Luciferase. |
CAS NO: | 10205-56-8 |
包装规格: | 5 MG |
产品类别: | 进口试剂 |
品牌: | Sigma-Aldrich |
优惠价: | 立即咨询 |
产品价格查看更多规格...
产品编号 | 包装单位 | 单价(元) | 国内现货 | 国外库存 | 询价单 |
4083895 | 5 MG | 2150 |
产品别名
10205-56-8
Luciferase Inhibitor II-CAS 10205-56-8-Calbiochem
4-(1,3-Benzothiazol-2-yl)-N,N-dimethylaniline
基本信息
Empirical Formula【经验(实验)分子式】 | C15H14N2S |
Molecular weight | 254.35 |
General description【一般描述】 | A 2-arylbenzothiazole compound that acts as an inhibitor against the ATP-dependent Photinus pyralis (lucPpy) and Photuris pennsylvanica (lucPpe) luciferase activity (IC50 = 0.2 and 0.32 µM, respectively, with 10 µM ATP, 10 µM luciferin, and 10 nM respective enzyme). Unlike Luciferase Inhibitor I (Cat. No. 119113), Luciferase Inhibitor II is competitive with respect to luciferin and exhibits reduced potency against lucPpe-based commercial luciferase-luciferin formulations with high luciferin concentration (IC50 = 10 µM against Promega′s Kinase-Glo A 2-arylbenzothiazole compound that acts as an inhibitor against the ATP-dependent Photinus pyralis (lucPpy) and Photuris pennsylvanica (lucPpe) luciferase activity (IC50 = 0.2 and 0.32 µM, respectively, with 10 µM ATP, 10 µM luciferin, and 10 nM respective enzyme). Unlike Luciferase Inhibitor I (Cat. No. 119113), Luciferase Inhibitor II is competitive with respect to luciferin and exhibits reduced potency against lucPpe-based commercial luciferase-luciferin formulations with high luciferin concentration (IC50 = 10 µM against Promega′s Kinase-Glo |
Warning【警告】 | Toxicity: Harmful (C) |
Reconstitution【重悬】 | Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C. |
Other Notes【其他说明】 | Auld, D.S., et al. 2009. J. Med. Chem.52, 1450. Auld, D.S., et al. 2008. J. Med. Chem.51, 2372. |
Legal Information【法律信息】 | Marketed by Promega Corp. under the registered trademarks. CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany |
产品性质
Quality Level【质量水平】 | 100 |
Assay【测定】 | ≥95% (HPLC) |
form【形式】 | solid |
manufacturer/tradename | Calbiochem® |
storage condition【储存条件】 | OK to freeze protect from light |
color【颜色】 | pale green |
solubility【溶解性】 | DMSO: 0.5 mg/mL ethanol: 3 mg/mL |
shipped in【运输】 | ambient |
storage temp.【储存温度】 | 2-8℃ |
InChI | 1S/C15H14N2S/c1-17(2)12-9-7-11(8-10-12)15-16-13-5-3-4-6-14(13)18-15/h3-10H,1-2H3 |
InChI key | HYKGLCSXVAAXNC-UHFFFAOYSA-N |
packaging【包装】 | 5 mg in Glass bottle Packaged under inert gas |
安全信息
Storage Class Code【储存分类代码】 | 11 - Combustible Solids |
WGK | WGK 3 |