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MMP-2/MMP-9 Inhibitor I-CAS 193807-58-8-Calbiochem
| 产品编号： | 4083905 |
| 规格： | The MMP-2/MMP-9 Inhibitor I, also referenced under CAS 193807-58-8, controls the biological activity of MMP-2/MMP-9. This small molecule/inhibitor is primarily used for Protease Inhibitors applications. |
| CAS NO： | 193807-58-8 |
| 包装规格： | 5 MG |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品别名
193807-58-8
MMP-2/MMP-9 Inhibitor I-CAS 193807-58-8-Calbiochem
(2R)-2-[(4-Biphenylylsulfonyl)amino]-3-phenylpropionic Acid
基本信息
| Empirical Formula【经验(实验)分子式】 | C21H19NO4S |
| Molecular weight | 381.44 |
| General description【一般描述】 | A potent inhibitor of MMP-2 (gelatinase A; IC50 = 310 nM) and MMP-9 (gelatinase B; IC50 = 240 nM). A potent inhibitor of MMP-2 (IC50 = 310 nM) and MMP-9 (IC50 = 240 nM). Orally active in animal models of tumor growth and metastasis. |
| Biochem/physiol Actions【生化/生理作用】 | Primary Target MMP-2, MMP-9 Product does not compete with ATP. Reversible: no Cell permeable: no Target IC50: 310 nM and 240 nM against MMP-2 and MMP-9 |
| Warning【警告】 | Toxicity: Standard Handling (A) |
| Reconstitution【重悬】 | Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C. |
| Other Notes【其他说明】 | Tamura, Y., et al. 1998. J. Med. Chem.41, 640. |
| Legal Information【法律信息】 | CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany |
产品性质
| Quality Level【质量水平】 | 100 |
| Assay【测定】 | ≥95% (HPLC) |
| form【形式】 | solid |
| manufacturer/tradename | Calbiochem® |
| storage condition【储存条件】 | OK to freeze |
| color【颜色】 | white |
| solubility【溶解性】 | DMSO: 200 mg/mL |
| shipped in【运输】 | ambient |
| storage temp.【储存温度】 | −20℃ |
| packaging【包装】 | 5 mg in Plastic ampoule Packaged under inert gas |
安全信息
| Storage Class Code【储存分类代码】 | 11 - Combustible Solids |
| WGK | WGK 1 |
