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Biotin-SLF
产品别名
2230857-85-7
Biotin-SLF
(R)-3-(3,4-Dimethoxyphenyl)-1-(3-(4,18-dioxo-22-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)-8,11,14-trioxa-5,17-diazadocosanamido)phenyl)propyl (S)-1-(3,3-dimethyl-2-oxopentanoyl)piperidine-2-carboxylate
Biotin-conjugated FKBP12WT-directed ligand
Biotin-conjugated SLF ligand
FKBP12WT affinity probe for PROTAC and targeted protein degradation research
Bio-SLF
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 | C52H76N6O13S |
| Molecular weight | 1025.26 |
| Application【应用】 | Biotin-SLF (bio-SLF) is an FKBP12WT affinity probe useful in chemical biology or targeted protein degradation where FKBP12 is used as a tool protein and its enrichment is required in discovery experiments or assay validation. Related tools: Additional bifunctional tools for FKPB12 variants:
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| Other Notes【其他说明】 | The dTAG system for immediate and target-specific protein degradation Technology Spotlight: Building PROTAC® Degraders for Targeted Protein Degradation |
| Legal Information【法律信息】 | PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license |
产品性质
| form【形式】 | powder |
| Quality Level【质量水平】 | 100 |
| storage temp.【储存温度】 | −20℃ |
| SMILES string | O=C(CCC(NCCOCCOCCOCCNC(CCCC[C@@H]1SC[C@@](N2)([H])[C@]1([H])NC2=O)=O)=O)NC3=CC([C@H](OC([C@@H]4CCCCN4C(C(C(C)(C)CC)=O)=O)=O)CCC5=CC=C(OC)C(OC)=C5)=CC=C3 O=C(CCC(NCCOCCOCCOCCNC(CCCC[C@@H]1SC[C@@](N2)([H])[C@]1([H])NC2=O)=O)=O)NC3=CC([C@H](OC([C@@H]4CCCCN4C(C(C(C)(C)CC)=O)=O)=O)CCC5=CC=C(OC)C(OC)=C5)=CC=C3 |
安全信息
| Storage Class Code【储存分类代码】 | 10 - Combustible liquids |
| WGK | WGK 3 |
