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Bavachin

产品编号:4084383
规格:from Psoralea coryfolia, ≥97% (HPLC)
CAS NO:19879-32-4
包装规格:5 MG
产品类别:进口试剂
品牌:Sigma-Aldrich
优惠价:立即咨询
产品编号包装单位单价(元)国内现货国外库存询价单
40843835 MG1570
产品别名

19879-32-4

Bavachin

(2S)-2,3-Dihydro-7-hydroxy-2-(4-hydroxyphenyl)-6-(3-methyl-2-butenyl)-4H-1-benzopyran-4-one

Corylifolin

4′,7-Dihydroxy 6-(3-methyl 2-butenyl)flavanone

结构式
基本信息
Empirical Formula【经验(实验)分子式】
C20H20O4
Molecular weight
324.37
MDL number
MFCD11617359
Biochem/physiol Actions【生化/生理作用】
Bavachin is a flavonoid isolated from seeds of Psoralea corylifolia. It is a phytoestrogen that activates ERα and ERβ (EC50s = 320 and 680 nM, respectively), stimulates osteoblast proliferation and differentiation, and prevents bone loss following ovariectomy in rats.

Bavachin is an inhibitor of acyl coenzyme A: cholesterol acyltransferase (ACAT). The IC50 value of bavachin was reported to be 86.0 μM in ACAT assay system using rat liver microsome.

Bavachin is also reported to increase insulin-induced glucose uptake by differentiated adipocytes and myoblasts.
Physical properties【物理属性】
Bavachin is soluble in DMSO at 30 mg/mL. Bavachin is not water soluble.
产品性质
Assay【测定】
≥97% (HPLC)
form【形式】
powder
storage temp.【储存温度】
−20℃
安全信息
Pictograms【象形图】
GHS07
Signal word【警示用语:】
Warning
Hazard Statements
H302 + H312 + H332
Precautionary Statements
P280 - P301 + P312 + P330 - P302 + P352 + P312 - P304 + P340 + P312
Hazard Classifications【危险分类】
Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral
Storage Class Code【储存分类代码】
11 - Combustible Solids
WGK
WGK 3
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