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Interleukin-2 Soluble Receptor α human
| 产品编号： | 4084390 |
| 规格： | >97% (SDS-PAGE), recombinant, expressed in NSO cells, lyophilized powder |
| 包装规格： | 5 μG |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品别名
Interleukin-2 Soluble Receptor α human
IL-2 sRα
TAC antigen
CD25
基本信息
| MDL number | MFCD01323736 |
| NACRES | NA.32 |
| Biochem/physiol Actions【生化/生理作用】 | Interleukin-2 (IL-2), a cytokine, enhances Th (T helper) cell differentiation and effector responses. In addition, it helps in immune tolerance. IL-2 binds to the high affinity receptor, formed of IL2RA (interleukin 2 receptor subunit α), IL2RB (interleukin 2 receptor subunit β) and γ-chain. Polymorphism in IL2RA is associated with multiple sclerosis. Null mutation in IL2RA results in immune dysregulation. |
| Physical form【外形】 | Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline containing 0.25 mg bovine serum albumin. |
| Analysis Note【分析说明】 | The bioactivity is measured by its ability to inhibit the IL-2-dependent proliferation of a human megakaryocytic leukemic cell line, M07e. |
产品性质
| Quality Level【质量水平】 | 200 |
| biological source【生物来源】 | human |
| recombinant【重组】 | expressed in NSO cells |
| Assay【测定】 | >97% (SDS-PAGE) |
| form【形式】 | lyophilized powder |
| potency【效能】 | 0.5-1.0 mg per mL ED50 |
| mol wt【分子量】 | 36 kDa by SDS-PAGE |
| packaging【包装】 | pkg of 5 μg |
| impurities【杂质】 | endotoxin, tested |
| UniProt accession no.【UniProt登记号】 | P01589 |
| storage temp.【储存温度】 | −20℃ |
| Gene Information | human ... IL2RA(3559) |
安全信息
| Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
