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Protein Kinase Cν (PKCν) Active human
| 产品编号： | 4084489 |
| 规格： | recombinant, expressed in E. coli, ≥75% (SDS-PAGE), buffered aqueous glycerol solution |
| 包装规格： | 5 μG |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品别名
Protein Kinase Cν (PKCν) Active human
Protein Kinase C nu
PKD3
基本信息
| MDL number | MFCD07371119 |
| NACRES | NA.32 |
| Application【应用】 | Kinase activity is measured as the molar amount of phosphate incorporated into the CREBtide substrate peptide (KRREILSRRPSYR) per minute per mg protein at 30 ℃ using a final concentration of 50 μM [32P] ATP. |
| Biochem/physiol Actions【生化/生理作用】 | PKCν, also known as PKD3, is a member of the protein kinase C (PKC) family of serine/threonine kinases that play critical roles in the regulation of cellular differentiation and proliferation in many cell types. PKCν is an important physiologic target of the B-cell receptor (BCR) and exhibits activation upon BCR engagement. |
| Physical form【外形】 | Solution of 5 μg in 50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 0.25 mM DTT, 0.1 mM EGTA, and 30% glycerol |
产品性质
| Quality Level【质量水平】 | 200 |
| recombinant【重组】 | expressed in E. coli |
| Assay【测定】 | ≥75% (SDS-PAGE) |
| form【形式】 | buffered aqueous glycerol solution |
| mol wt【分子量】 | protein apparent mol wt ~142 kDa |
| UniProt accession no.【UniProt登记号】 | O94806 |
| shipped in【运输】 | dry ice |
| storage temp.【储存温度】 | −70℃ |
| Gene Information | human ... PRKD3(23683) |
