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20:0(2R-OH) Ceramide

产品编号:4084556
规格:N-(2′-(R)-hydroxyarachidoyl)-D-erythro-sphingosine, powder
CAS NO:943147-54-4
包装规格:5 MG
产品类别:进口试剂
品牌:Avanti
优惠价:立即咨询
产品编号包装单位单价(元)国内现货国外库存询价单
40845565 MG3200
产品别名

943147-54-4

20:0(2R-OH) Ceramide

结构式
基本信息
Empirical Formula【经验(实验)分子式】
C38H75NO4
Molecular weight
610.01
NACRES
NA.25
General description【一般描述】
Ceramides containing 2-hydroxy fatty acids (hFA) group are mainly found in the epidermis. 20:0(2R-OH) Ceramide is a 2R hydroxylated arachidic acid-containing ceramide.
Biochem/physiol Actions【生化/生理作用】
Hydroxy fatty acid (hFA)-sphingolipids play a vital role in cell signaling. hFA-ceramides contribute to the permeability barrier function of the surface epithelium of the skin. Fatty acid 2-hydroxylase (FA2H) catalyzes the synthesis of hFA-ceramides. Impaired function of FA2H causes nervous system disorders leukodystrophy and spastic paraparesis in humans. hFA-ceramides are essential for PM02734, an antitumor drug to exhibit its activity.
产品性质
form【形式】
powder
manufacturer/tradename
Avanti Polar Lipids 860819P
shipped in【运输】
dry ice
storage temp.【储存温度】
−20℃
SMILES string
CCCCCCCCCCCCC/C=C/[C@@H](O)[C@@H](NC([C@H](O)CCCCCCCCCCCCCCCCCC)=O)CO
packaging【包装】
5 mL Amber Glass Screw Cap Vial (860819P-5mg)
安全信息
Storage Class Code【储存分类代码】
13 - Non Combustible Solids
WGK
WGK 3
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