您的位置：首页 > 产品中心 > Anti-acetyl Histone H4 (Lys5/8/12/16) Antibody, clone 3HH4-4C10
Anti-acetyl Histone H4 (Lys5/8/12/16) Antibody, clone 3HH4-4C10
| 产品编号： | 4084610 |
| 规格： | ascites fluid, clone 3HH4-4C10, from mouse |
| 包装规格： | 100 μL |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品别名
Anti-acetyl Histone H4 (Lys5/8/12/16) Antibody, clone 3HH4-4C10
H4KAc, Histone H4 (acetyl), H4 histone family, member N, H4 histone, family 2, histone 2, H4, histone 2, H4a, histone IV, family 2, histone cluster 2, H4a
基本信息
| eCl@ss | 32160702 |
| NACRES | NA.41 |
| General description【一般描述】 | Histone H4 is one of the 5 main histone proteins involved in the structure of chromatin in eukaryotic cells. Featuring a main globular domain and a long N terminal tail H4 is involved with the structure of the nucleosomes of the ′beads on a string′ structure. Acetylation of histone H4 occurs at several different lysine positions in the histone tail and is performed by a family of enzymes known as Histone Acetyl Transferases (HATs). Posttranslational acetylation of the conserved core histone N-terminal tail domains is typically associated with gene activation. |
| Specificity【特异性】 | This antibody recognizes Histone H4. |
| Immunogen【免疫原】 | Linear peptide corresponding to human Histone H4 acetylated at Lys5/8/12/16. Epitope: Lys5/8/12/16 |
| Application【应用】 | Immunocytochemistry Analysis: 1:500 dilution from a representative lot detected Histone H4 in A431 and HeLa cells. Use Anti-acetyl Histone H4 (Lys5/8/12/16) Antibody, clone 3HH4-4C10 (mouse monoclonal antibody) validated in WB, ICC to detect acetyl Histone H4 (Lys5/8/12/16) also known as H4KAc, Histone H4 (acetyl). Research Sub Category Histones Research Category Epigenetics & Nuclear Function |
| Quality【质量】 | Evaluated by Western Blot in HeLa acid extract lysate. Western Blot Analysis: 1:2,000 dilution of this antibody detected Histone H4 on 10 µg of HeLa acid extract lysate. |
| Physical form【外形】 | Unpurified Unpurified mouse monoclonal IgG1κ preservative-free ascites. |
| Analysis Note【分析说明】 | Control HeLa acid extract lysate |
产品性质
| Quality Level【质量水平】 | 100 |
| biological source【生物来源】 | mouse |
| antibody form【抗体形式】 | ascites fluid |
| antibody product type | primary antibodies |
| clone【克隆】 | 3HH4-4C10, monoclonal |
| species reactivity | human |
| species reactivity (predicted by homology) | mouse (based on 100% sequence homology), rat (based on 100% sequence homology) |
| technique(s) | immunocytochemistry: suitable western blot: suitable |
| isotype【同位素/亚型】 | IgG1κ |
| NCBI accession no.【NCBI登记号】 | NP_778224 |
| UniProt accession no.【UniProt登记号】 | P62805 |
| shipped in【运输】 | dry ice |
产品说明
| Target description【目标描述】 | ~ 13 kDa |
| Storage and Stability【储存及稳定性】 | Stable for 1 year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance. |
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | WGK 1 |
