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Anti-CAR Antibody, clone RmcB
产品别名
Anti-CAR Antibody, clone RmcB
46 kD coxsackievirus and adenovirus receptor (CAR) protein, CVB3 binding protein, CVB3-binding protein, Coxsackievirus B-adenovirus receptor, coxsackie virus B receptor, coxsackie virus and adenovirus receptor
基本信息
| eCl@ss | 32160702 |
| NACRES | NA.41 |
| General description【一般描述】 | The coxsackievirus and adenovirus receptor (CAR) mediates cell attachment and infection by coxsackie B viruses and by a number of adenoviruses. CAR also mediates homotypic intercellular interactions. In polarized epithelial cells, CAR is closely associated with the tight junction, where it contributes to the barrier to paracellular flow of solutes and macromolecules. CAR′s biological roles are not well defined, but emerging evidence suggests that it may function during embryonic development and in regulating cell proliferation. |
| Specificity【特异性】 | Recognizes CAR at MW ~46 kDa. |
| Immunogen【免疫原】 | Native human coxsackie virus-adenovirus receptor protein. |
| Application【应用】 | Anti-CAR Antibody, clone RmcB detects level of CAR & has been published & validated for use in IC & WB. Immunocytochemistry: 1-2 μg/mL of a previous lot showed positive immunostaining for CAR in HeLa cells, hCAR transfected CHO cells, but not in untransfected CHO cells fixed with 4% paraformaldehyde and permeabilized with 0.2% Triton-X. |
| Quality【质量】 | Evaluated by Western Blot on mouse small intestine lysates. Western Blot Analysis: 1:500 dilution of this antibody detected Car on 10 µg of mouse small intestine lysates. |
| Physical form【外形】 | Purified mouse monoclonal IgG1 in buffer containing 0.1M Tris-Glycine, 0.15M NaCl and 0.05% Sodium Azide, pH 7.4. Protein G Purified Format: Purified |
| Other Notes【其他说明】 | Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration. |
| Legal Information【法律信息】 | UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany |
产品性质
| Quality Level【质量水平】 | 100 |
| biological source【生物来源】 | mouse |
| antibody form【抗体形式】 | purified immunoglobulin |
| antibody product type | primary antibodies |
| clone【克隆】 | RmcB, monoclonal |
| species reactivity | human, rat, mouse |
| manufacturer/tradename | Upstate® |
| technique(s) | immunocytochemistry: suitable western blot: suitable |
| isotype【同位素/亚型】 | IgG1 |
| NCBI accession no.【NCBI登记号】 | NM_001338 |
| UniProt accession no.【UniProt登记号】 | P78310 |
| shipped in【运输】 | wet ice |
| Gene Information | human ... CXADR(1525) |
产品说明
| Target description【目标描述】 | ~46 kDa |
| 【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 10 - Combustible liquids |
| WGK | WGK 1 |
