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Anti-monomethyl Histone H3 (Lys9) Antibody, clone CMA306
产品别名
Anti-monomethyl Histone H3 (Lys9) Antibody, clone CMA306
H3K9me1, Histone H3 (mono methyl K9), H3-K9-HMTase 1, Histone H3-K9 methyltransferase 1, Lysine N-methyltransferase 1A, Position-effect variegation 3-9 homolog, Su(var)3-9 homolog 1, Suppressor of variegation 3-9 homolog 1, histone-lysine N-methyltransfe
基本信息
| eCl@ss | 32160702 |
| NACRES | NA.41 |
| General description【一般描述】 | Histone H3 is one of the five main histone proteins involved in the structure of chromatin in eukaryotic cells. Featuring a main globular domain and a long N-terminal tail, H3 is involved with the structure of the nucleosomes of the ′beads on a string′ structure. The N-terminal tail of histone H3 protrudes from the globular nucleosome core and can undergo several different types of epigenetic modifications that influence cellular processes. These modifications include the covalent attachment of methyl or acetyl groups to lysine and arginine amino acids and the phosphorylation of serine or threonine. |
| Specificity【特异性】 | This antibody recognizes monomethylated Lys9 at and around the N-terminal of Histone H3. |
| Immunogen【免疫原】 | KLH conjugated linear peptide corresponding to monomethylated Lys9 at the N-terminal region of Histone H3. Epitope: monomethylated H3 Lys9 |
| Application【应用】 | Dot Blot Analysis: AbSurance Peptide Inhibition: Representative lot data. Specificity confirmed by the ability of immunizing peptide to abolish detection of monomethyl Histone H3 (Lys9) (Lane 7) in western blot analysis of HeLa acid extracts and various other modified histone peptides. Research Sub Category Histones Research Category Epigenetics & Nuclear Function Use Anti-monomethyl Histone H3 (Lys9) Antibody, clone CMA306 (Mouse Monoclonal Antibody) validated in WB, PIA to detect monomethyl Histone H3 (Lys9) also known as H3K9me1. |
| Quality【质量】 | Evaluated by Western Blot on recombinant Histone H3 and HeLa acid extract. Western Blot Analysis: 1 µg/mL of this antibody detected Histone H3 in 500 ng of recombinant Histone H3 and 10 µg of HeLa acid extract. |
| Physical form【外形】 | Format: Purified Purified mouse monoclonal IgG2a in PBS with 0.05% sodium azide. Protein G Purified |
| Analysis Note【分析说明】 | Control Recombinant Histone H3 and HeLa acid extract. |
| Other Notes【其他说明】 | Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration. |
产品性质
| Quality Level【质量水平】 | 100 |
| biological source【生物来源】 | mouse |
| antibody form【抗体形式】 | purified immunoglobulin |
| antibody product type | primary antibodies |
| clone【克隆】 | CMA306, monoclonal |
| species reactivity | human |
| technique(s) | inhibition assay: suitable (peptide) western blot: suitable |
| isotype【同位素/亚型】 | IgG2a |
| NCBI accession no.【NCBI登记号】 | NP_003484 |
| UniProt accession no.【UniProt登记号】 | O43463 |
| shipped in【运输】 | wet ice |
产品说明
| Target description【目标描述】 | ~17 kDa |
| Storage and Stability【储存及稳定性】 | Stable at 2-8°C for 1 year from date of receipt. |
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 10 - Combustible liquids |
| WGK | WGK 2 |
