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C8 Ceramide (d18:1/8:0)
| 产品编号： | 4084787 |
| 规格： | N-octanoyl-D-erythro-sphingosine, powder |
| CAS NO： | 74713-59-0 |
| 包装规格： | 5 MG |
| 产品类别： | 进口试剂 |
| 品牌： | Avanti |
| 优惠价： | 立即咨询 |
产品价格查看更多规格...
| 产品编号 | 包装单位 | 单价(元) | 国内现货 | 国外库存 | 询价单 |
| 4084787 | 5 MG | 1130 |
产品别名
74713-59-0
C8 Ceramide (d18:1/8:0)
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 | C26H51NO3 |
| Molecular weight | 425.69 |
| NACRES | NA.25 |
| General description【一般描述】 | C8 Ceramide is a short chain ceramide and is cell permeable. |
| Application【应用】 | C8 Ceramide (d18:1/8:0) has been used as an internal ceramide standard in electrospray ionization. It has also been used as a substrate for ceramide kinase activity assay. It is suitable for use as a substrate for galactocerebrosidase. |
| Biochem/physiol Actions【生化/生理作用】 | C8 Ceramide has anti-tumor functionality. Synthetic liposomal C8 ceramide inhibits hepatocellular carcinoma (HCC). Addition of exogenous C8 ceramide causes necrosis in hepatocytes by decreasing ATP levels and impairing mitochondrial functionality. C8 ceramide inhibition of serine palmitoyl transferase halts de novo sphingolipid biosynthesis. It also acts as chemotherapeutic agent by increasing the reactive oxygen species in lung cancer cells. |
产品性质
| form【形式】 | powder |
| manufacturer/tradename | Avanti Polar Lipids 860508P |
| shipped in【运输】 | dry ice |
| storage temp.【储存温度】 | −20℃ |
| SMILES string | OC[C@]([H])(NC(CCCCCCC)=O)[C@]([H])(O)/C=C/CCCCCCCCCCCCC |
| packaging【包装】 | 5 mL Amber Glass Screw Cap Vial (860508P-5mg) |
安全信息
| Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |
