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C8 Ceramide (d18:1/8:0)

产品编号:4084787
规格:N-octanoyl-D-erythro-sphingosine, powder
CAS NO:74713-59-0
包装规格:5 MG
产品类别:进口试剂
品牌:Avanti
优惠价:立即咨询
产品编号包装单位单价(元)国内现货国外库存询价单
40847875 MG1130
产品别名

74713-59-0

C8 Ceramide (d18:1/8:0)

结构式
基本信息
Empirical Formula【经验(实验)分子式】
C26H51NO3
Molecular weight
425.69
NACRES
NA.25
General description【一般描述】
C8 Ceramide is a short chain ceramide and is cell permeable.
Application【应用】
C8 Ceramide (d18:1/8:0) has been used as an internal ceramide standard in electrospray ionization. It has also been used as a substrate for ceramide kinase activity assay. It is suitable for use as a substrate for galactocerebrosidase.
Biochem/physiol Actions【生化/生理作用】
C8 Ceramide has anti-tumor functionality. Synthetic liposomal C8 ceramide inhibits hepatocellular carcinoma (HCC). Addition of exogenous C8 ceramide causes necrosis in hepatocytes by decreasing ATP levels and impairing mitochondrial functionality. C8 ceramide inhibition of serine palmitoyl transferase halts de novo sphingolipid biosynthesis. It also acts as chemotherapeutic agent by increasing the reactive oxygen species in lung cancer cells.
产品性质
form【形式】
powder
manufacturer/tradename
Avanti Polar Lipids 860508P
shipped in【运输】
dry ice
storage temp.【储存温度】
−20℃
SMILES string
OC[C@]([H])(NC(CCCCCCC)=O)[C@]([H])(O)/C=C/CCCCCCCCCCCCC
packaging【包装】
5 mL Amber Glass Screw Cap Vial (860508P-5mg)
安全信息
Storage Class Code【储存分类代码】
13 - Non Combustible Solids
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