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N-CoR human
| 产品编号： | 4084878 |
| 规格： | recombinant, expressed in insect cells, ≥60% (SDS-PAGE) |
| 包装规格： | 5 μG |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品别名
N-CoR human
MGC104216
N-CoR
N-CoR1
hN-CoR
TRAC1
KIAA1047
产品性质
| biological source【生物来源】 | human |
| recombinant【重组】 | expressed in insect cells |
| Assay【测定】 | ≥60% (SDS-PAGE) |
| form【形式】 | frozen liquid |
| mol wt【分子量】 | ~271 kDa |
| packaging【包装】 | pkg of 5 μg |
| concentration【浓度】 | 700 μg/mL |
| technique(s) | deacetylase assay: suitable |
| color【颜色】 | clear colorless |
| NCBI accession no.【NCBI登记号】 | NM_006311 |
| UniProt accession no.【UniProt登记号】 | O75376 |
| shipped in【运输】 | dry ice |
| storage temp.【储存温度】 | −70℃ |
| Gene Information | human ... NCOR1(9611) |
基本信息
| Biochem/physiol Actions【生化/生理作用】 | This gene encodes a protein that mediates ligand-independent transcription repression of thyroid-hormone and retinoic-acid receptors by promoting chromatin condensation and preventing access of the transcription machinery. It is part of a complex which also includes histone deacetylases and transcriptional regulators similar to the yeast protein Sin3p. This gene is located between the Charcot-Marie-Tooth and Smith-Magenis syndrome critical regions on chromosome 17. An alternatively spliced transcript variant has been described, but its full length sequence has not been determined |
| Physical form【外形】 | Clear and colorless frozen liquid solution |
| Preparation Note【制备说明】 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. While working, please keep sample on ice. |
安全信息
| Storage Class Code【储存分类代码】 | 10 - Combustible liquids |
| WGK | WGK 1 |
