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Anti-Fibroblast Growth Factor Receptor 1 Antibody, clone VBS1
产品别名
Anti-Fibroblast Growth Factor Receptor 1 Antibody, clone VBS1
CD331 antigen, Fms-like tyrosine kinase 2, basic fibroblast growth factor receptor 1, fibroblast growth factor receptor 1, fms-related tyrosine kinase 2, heparin-binding growth factor receptor, hydroxyaryl-protein kinase, soluble FGFR1 variant 1, soluble
基本信息
| eCl@ss | 32160702 |
| NACRES | NA.41 |
| General description【一般描述】 | The fibroblast growth factor receptors are members of the tyrosine kinase superfamily and consist of an extracellular ligand domain composed of three immunoglobulin-like domains, a single transmembrane helix domain, and an intracellular domain with tyrosine kinase activity. (Ornitz, DM. and Itoh, N) Monoclonal antibodies against the high affinity tyrosine kinase Fibroblast Growth Factor (FGF) receptor may help define receptor epitopes involved in FGF binding and signal transduction which mediate coronary and tumor angiogenesis. (Venkateswaran, S., et al). |
| Specificity【特异性】 | This antibody recognizes the extracellular ligand-binding domain of Fibroblast Growth Factor Receptor 1. |
| Immunogen【免疫原】 | FGF Receptor purified from bovine coronary venular endothelial cells. Epitope: Extracellular |
| Application【应用】 | Detect Fibroblast Growth Factor Receptor 1 using this Anti-Fibroblast Growth Factor Receptor 1 Antibody, clone VBS1 validated for use in WB, IP, IH(P), ELISA. Research Sub Category Growth Factors & Receptors Immunohistochemistry Analysis: A previous lot was used by an independent laboratory in IH(P) (Venkateswaran, S., et al) Research Category Signaling |
| Quality【质量】 | Evaluated by Western Blotting in NIH/3T3 cell lysate. Western Blotting Analysis: 0.78 µg/mL of this antibody detected Fibroblast Growth Factor Receptor 1 in 10 µg of NIH/3T3 cell lysate. |
| Linkage【联系】 | Replaces: MAB125 |
| Physical form【外形】 | Format: Purified Protein A purified Purified mouse monoclonal IgM in 0.015 M potassium phosphate buffer containing 0.15 M NaCl, 0.1% sodium azide, pH 7.20. |
| Analysis Note【分析说明】 | Control NIH/3T3 cell lysate |
| Other Notes【其他说明】 | Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration. |
产品性质
| Quality Level【质量水平】 | 100 |
| biological source【生物来源】 | mouse |
| antibody form【抗体形式】 | purified immunoglobulin |
| antibody product type | primary antibodies |
| clone【克隆】 | VBS1, monoclonal |
| species reactivity | mouse, rat, bovine, chicken, human |
| technique(s) | ELISA: suitable immunohistochemistry: suitable (paraffin) immunoprecipitation (IP): suitable western blot: suitable |
| isotype【同位素/亚型】 | IgM |
| NCBI accession no.【NCBI登记号】 | NP_001103677.1 |
| UniProt accession no.【UniProt登记号】 | P11362 |
| shipped in【运输】 | wet ice |
产品说明
| Target description【目标描述】 | ~92 kDa |
| Storage and Stability【储存及稳定性】 | Stable for 1 year at 2-8°C from date of receipt. |
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | WGK 2 |
