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Anti-RING1 Antibody, clone 4D6
产品别名
Anti-RING1 Antibody, clone 4D6
Polycomb complex protein RING1, ring finger protein 1
基本信息
| eCl@ss | 32160702 |
| NACRES | NA.41 |
| General description【一般描述】 | RING1 belongs to the RING finger family, members of which are characterized by a RING domain, a zinc-binding motif related to the zinc finger domain. The gene product can bind DNA and can act as a transcriptional repressor. It is associated with the multimeric polycomb group protein complex. The gene product interacts with the polycomb group proteins BMI1, EDR1, and CBX4, and colocalizes with these proteins in large nuclear domains. It interacts with the CBX4 protein via its glycine-rich C-terminal domain. |
| Specificity【特异性】 | This antibody detects RING1. |
| Immunogen【免疫原】 | GST-tagged recombinant protein corresponding to RING1. |
| Application【应用】 | Research Sub Category Transcription Factors Use Anti-RING1 Antibody, clone 4D6 (Mouse Monoclonal Antibody) validated in WB, ICC to detect RING1 also known as Polycomb complex protein RING1. Research Category Epigenetics & Nuclear Function Immunocytochemistry: Representative lot data. A 1:500 dilution of a previous lot was used in immunocytochemistry on NIH/3T3 and A431 cells. |
| Quality【质量】 | Evaluated by western blot on HEK293 cell lysate. Western Blot Analysis: 0.5-2 µg/mL of this antibody detected RING1 in HEK293 cell lysate. |
| Physical form【外形】 | Format: Purified Purified mouse monoclonal in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide. Protein G Purified |
| Analysis Note【分析说明】 | Control HEK293 cell lysate |
| Other Notes【其他说明】 | Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration. |
产品性质
| Quality Level【质量水平】 | 100 |
| biological source【生物来源】 | mouse |
| antibody form【抗体形式】 | purified antibody |
| antibody product type | primary antibodies |
| clone【克隆】 | 4D6, monoclonal |
| species reactivity | mouse, human |
| technique(s) | immunocytochemistry: suitable western blot: suitable |
| isotype【同位素/亚型】 | IgG2aκ |
| NCBI accession no.【NCBI登记号】 | NP_002922.2 |
| UniProt accession no.【UniProt登记号】 | Q06587 |
| shipped in【运输】 | wet ice |
产品说明
| Target description【目标描述】 | ~42 kDa |
| Storage and Stability【储存及稳定性】 | Stable for 1 year at 2-8ºC from date of receipt. |
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | WGK 1 |
