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Anti-VEGF Antibody, clone CH-10
| 产品编号： | 4085241 |
| 规格： | clone CH-10, from mouse, purified by affinity chromatography |
| 包装规格： | 100 μg |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品别名
Anti-VEGF Antibody, clone CH-10
Vascular permeability factor, vascular endothelial growth factor, vascular endothelial growth factor A, vascular endothelial growth factor isoform VEGF165
基本信息
| eCl@ss | 32160702 |
| NACRES | NA.41 |
| General description【一般描述】 | VEGF (Vascular endothelial growth factor, VEGFA, VEGF-A), a dimeric ligand, is among the most potent angiogenic mitogens. VEGF is secreted by tumor cells and other cells exposed to hypoxia. VEGF is a highly specific mitogen for vascular endothelial cells. Seven VEGF isoforms (a, b, c, d, e, f, g) are generated as a result of alternative splicing from a single VEGF gene. All seven isoforms differ in their molecular mass and in biological properties such as their ability to bind to cell-surface heparan-sulfate proteoglycans. The expression of VEGF is potentiated and is secreted by tumor cells in response to hypoxia, by activated oncogenes, and by a variety of cytokines. |
| Specificity【特异性】 | This antibody recognizes human and rat VEGF, other variants not tested. |
| Immunogen【免疫原】 | Recombinant mouse VEGF. |
| Application【应用】 | Anti-VEGF Antibody, clone CH-10 is an antibody against VEGF for use in WB. Research Sub Category Growth Factors & Receptors Research Category Signaling |
| Quality【质量】 | Evaluated by Western Blot in Jurkat cell lysate. Western Blot Analysis: 1:1000 dilution of this antibody detected VEGF on 10 µg of Jurkat cell lysate. |
| Linkage【联系】 | Replaces: MAB1665 |
| Physical form【外形】 | Liquid in 20 mM sodium phosphate, 250 mM NaCl, pH. 7.6 containing 0.1% sodium azide. Affinity purified |
| Analysis Note【分析说明】 | Control Jurkat cell lysate |
| Other Notes【其他说明】 | Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration. |
产品性质
| Quality Level【质量水平】 | 100 |
| biological source【生物来源】 | mouse |
| antibody form【抗体形式】 | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone【克隆】 | CH-10, monoclonal |
| purified by【纯化方式】 | affinity chromatography |
| species reactivity | rat, human |
| technique(s) | western blot: suitable |
| isotype【同位素/亚型】 | IgG1 |
| NCBI accession no.【NCBI登记号】 | NP_033531.3 |
| UniProt accession no.【UniProt登记号】 | P15692 |
| shipped in【运输】 | wet ice |
产品说明
| Target description【目标描述】 | 12/16/19 kDa |
| Storage and Stability【储存及稳定性】 | Stable for 1 year at 2-8°C from date of receipt. |
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 10 - Combustible liquids |
| WGK | WGK 2 |
