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Anti-α-Tubulin Antibody, clone DM1A, Alexa Fluor® 647 conjugate
| 产品编号： | 4085971 |
| 规格： | clone DM1A, from mouse, ALEXA FLUOR® 647 |
| 包装规格： | 100 μL |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品别名
Anti-α-Tubulin Antibody, clone DM1A, Alexa Fluor® 647 conjugate
Tubulin alpha-1 chain, α-Tubulin
基本信息
| eCl@ss | 32160702 |
| NACRES | NA.41 |
| General description【一般描述】 | Tubulin alpha-1 chain (UniProt P02552) is encoded by the TUBA1C (also known as TUBA1) gene (Gene ID 429035) in Gallus gallus (Chicken) species. Microtubules are cytoskeletal filaments composed of alpha-/beta-tubulin heterodimers that self-assemble head-to-tail to form protofilaments and laterally to form a hollow tube. Various post-translational modifications, including acetylation, polyglutamylation, polyglycylation, detyrosination, phosphorylation, and palmitoylation, can regulate the polymerization properties of tubulins and/or their interactions with microtubule associated proteins (MAPs) and motor proteins. |
| Specificity【特异性】 | Clone DM1A recognizes α-Tubulin, MW 50-60 kDa. The epitope recognized by clone DM1A has been mapped to the C-terminal 25 amino acids. |
| Immunogen【免疫原】 | Epitope: C-terminal 25 amino acids. Purified chicken brain α-Tubulin. The epitope recognized by this antibody has been mapped to the C-terminal 25 amino acids (AALEKDYEEVGVDSVEGEGEEEGEE). |
| Application【应用】 | Research Category Cell Structure Anti-α-Tubulin Antibody, clone DM1A, Alexa Fluor® 647 conjugate is an antibody against α-Tubulin for use in Immunocytochemistry. Immunocytochemistry Analysis: A 1:100 dilution from a representative lot detected α-Tubulin in NIH/3T3 cells. The unconjugated antibody (Cat. No. 05-829) is shown to be suitable also for immunocytochemistry, immunofluorescence, and Western blotting applications. Research Sub Category Cytoskeleton |
| Quality【质量】 | Evaluated by Immunocytochemistry in A431 cells. Immunocytochemistry Analysis: A 1:100 dilution of this antibody detected α-Tubulin in A431 cells. |
| Physical form【外形】 | Purified mouse monoclonal IgG1 antibody conjugate in PBS with 15 mg/mL BSA and 0.1 % sodium azide. Protein G Purified |
| Other Notes【其他说明】 | Concentration: Please refer to lot specific datasheet. |
| Legal Information【法律信息】 | ALEXA FLUOR is a registered trademark of Life Technologies |
产品性质
| Quality Level【质量水平】 | 100 |
| biological source【生物来源】 | mouse |
| conjugate【偶联物】 | ALEXA FLUOR® 647 |
| antibody form【抗体形式】 | purified immunoglobulin |
| antibody product type | primary antibodies |
| clone【克隆】 | DM1A, monoclonal |
| species reactivity | porcine, avian, rat, human, guinea pig, gerbil, bovine, mouse |
| technique(s) | immunocytochemistry: suitable |
| isotype【同位素/亚型】 | IgG1 |
| NCBI accession no.【NCBI登记号】 | NP_001292201.1 |
| UniProt accession no.【UniProt登记号】 | P02552 |
| shipped in【运输】 | wet ice |
产品说明
| Target description【目标描述】 | ~50 kDa observed. |
| Storage and Stability【储存及稳定性】 | Stable for 1 year at 2-8°C from date of receipt. |
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | WGK 2 |
