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ATN-161

产品编号:4085995
规格:≥98% (HPLC)
CAS NO:262438-43-7
包装规格:5 MG,25 MG
产品类别:进口试剂
品牌:Sigma-Aldrich
优惠价:立即咨询
产品编号包装单位单价(元)国内现货国外库存询价单
40859955 MG2010
408599525 MG5900
产品别名

262438-43-7

ATN-161

Ac-Pro-His-Ser-Cys-Asn-NH2, PHSCN (Modifications: Pro-1 = N-terminal Ac, Asn-5 = C-terminal amide)

Ac-PHSCN-NH2

1-Acetyl-L-prolyl-L-histidyl-L-seryl-L-cysteinyl-L-aspartamide

基本信息
Empirical Formula【经验(实验)分子式】
C23H35N9O8S
Molecular weight
597.64
NACRES
NA.77
Application【应用】
ATN-161 has been used as an inhibitor of integrin α5β1 and αvβ3 in cultured platelet endothelial cell adhesion molecule (PECAM1)-positive endothelial cells isolated from AL (CECAL).
Biochem/physiol Actions【生化/生理作用】
ATN-161 is a non-RGD based integrin binding peptide derived from the synergy region of fibronectin that inhibits the receptors for integrins alpha-v beta-3 and integrin alpha-5 beta-1. Integrin alpha-5 beta-1 is expressed on endothelial cells and plays a key role in endothelial cell adhesion and migration and may also play a key role in cancer cell invasion and metastasis. ATN-161 was shown to have antiangigenic and antitumor activity.
产品性质
Assay【测定】
≥98% (HPLC)
form【形式】
powder
color【颜色】
white to beige
shipped in【运输】
wet ice
storage temp.【储存温度】
−20℃
安全信息
Storage Class Code【储存分类代码】
11 - Combustible Solids
WGK
WGK 3
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