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BAY-707
产品别名
2109805-96-9
BAY-707
(S)-N-Ethyl-4-(3-methylmorpholino)-1H-pyrrolo[2,3-b]pyridine-2-carboxamide
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 | C15H20N4O2 |
| Molecular weight | 288.34 |
| Biochem/physiol Actions【生化/生理作用】 | BAY-707 is an inhibitor of the human 7,8-dihydro-8-oxoguaninetriphosphatase MTH1 (NUDT1), which hydrolyzes oxidized purine nucleoside triphosphates that might otherwise be incorporated into DNA/RNA and contribute to DNA damage. BAY-707 was shown to be a substrate-competitive, selective MTH1 inhibitor with an IC50 value of 2.3 nM. |
产品性质
| Assay【测定】 | ≥98% (HPLC) |
| form【形式】 | powder |
| color【颜色】 | white to beige |
| solubility【溶解性】 | DMSO: 2 mg/mL, clear |
| storage temp.【储存温度】 | 2-8℃ |
| SMILES string | O=C(NCC)C1=CC2=C(N1)N=CC=C2N3CCOC[C@@H]3C |
安全信息
| Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
