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CMPPE

产品编号:4086078
规格:≥95% (HPLC)
CAS NO:841253-81-4
包装规格:25 MG
产品类别:进口试剂
品牌:Sigma-Aldrich
优惠价:立即咨询
产品编号包装单位单价(元)国内现货国外库存询价单
408607825 MG4490
产品别名

841253-81-4

CMPPE

2-[1-[2-(4-Chlorophenyl)-5-methylpyrazol[1,5-a]pyrimidin-7-yl]-2-piperidinyl]ethanol

结构式
基本信息
Empirical Formula【经验(实验)分子式】
C20H23ClN4O
Molecular weight
370.88
MDL number
MFCD05710220
PubChem Substance ID【PubChem化学物质编号】
329825972
NACRES
NA.77
Biochem/physiol Actions【生化/生理作用】
CMPPE is a GABAB receptor positive allosteric modulator (PAM). GABAB receptor positive allosteric modulators have potential for treatment of many neuro-psychiatric disorders as well as drug dependence and seizures. The receptor is a GPCR expressed throughout the CNS; it acts as both an auto-receptor and heteroreceptor to mudulate GABA release and regulate K+ channels and Ca++ channels. CMPPE has the highest hypoactivity/anticonvulsant ratio.
产品性质
Quality Level【质量水平】
100
Assay【测定】
≥95% (HPLC)
form【形式】
powder
color【颜色】
white to light brown
solubility【溶解性】
DMSO: 5 mg/mL, clear (warmed)
storage temp.【储存温度】
2-8℃
SMILES string
ClC(C=C1)=CC=C1C2=NN(C(N3C(CCO)CCCC3)=CC(C)=N4)C4=C2
InChI
1S/C20H23ClN4O/c1-14-12-20(24-10-3-2-4-17(24)9-11-26)25-19(22-14)13-18(23-25)15-5-7-16(21)8-6-15/h5-8,12-13,17,26H,2-4,9-11H2,1H3
InChI key
TZWSGOPCLUTFBZ-UHFFFAOYSA-N
packaging【包装】
5, 25 mg in glass bottle
安全信息
Pictograms【象形图】
GHS07
Signal word【警示用语:】
Warning
Hazard Statements
H302
Precautionary Statements
P301 + P312 + P330
Hazard Classifications【危险分类】
Acute Tox. 4 Oral
Storage Class Code【储存分类代码】
13 - Non Combustible Solids
WGK
WGK 3
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