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CMPPE
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产品编号 | 包装单位 | 单价(元) | 国内现货 | 国外库存 | 询价单 |
4086078 | 25 MG | 4490 |
产品别名
841253-81-4
CMPPE
2-[1-[2-(4-Chlorophenyl)-5-methylpyrazol[1,5-a]pyrimidin-7-yl]-2-piperidinyl]ethanol
结构式
基本信息
Empirical Formula【经验(实验)分子式】 | C20H23ClN4O |
Molecular weight | 370.88 |
MDL number | MFCD05710220 |
PubChem Substance ID【PubChem化学物质编号】 | 329825972 |
NACRES | NA.77 |
Biochem/physiol Actions【生化/生理作用】 | CMPPE is a GABAB receptor positive allosteric modulator (PAM). GABAB receptor positive allosteric modulators have potential for treatment of many neuro-psychiatric disorders as well as drug dependence and seizures. The receptor is a GPCR expressed throughout the CNS; it acts as both an auto-receptor and heteroreceptor to mudulate GABA release and regulate K+ channels and Ca++ channels. CMPPE has the highest hypoactivity/anticonvulsant ratio. |
产品性质
Quality Level【质量水平】 | 100 |
Assay【测定】 | ≥95% (HPLC) |
form【形式】 | powder |
color【颜色】 | white to light brown |
solubility【溶解性】 | DMSO: 5 mg/mL, clear (warmed) |
storage temp.【储存温度】 | 2-8℃ |
SMILES string | ClC(C=C1)=CC=C1C2=NN(C(N3C(CCO)CCCC3)=CC(C)=N4)C4=C2 |
InChI | 1S/C20H23ClN4O/c1-14-12-20(24-10-3-2-4-17(24)9-11-26)25-19(22-14)13-18(23-25)15-5-7-16(21)8-6-15/h5-8,12-13,17,26H,2-4,9-11H2,1H3 |
InChI key | TZWSGOPCLUTFBZ-UHFFFAOYSA-N |
packaging【包装】 | 5, 25 mg in glass bottle |
安全信息
Pictograms【象形图】 | GHS07 |
Signal word【警示用语:】 | Warning |
Hazard Statements | H302 |
Precautionary Statements | P301 + P312 + P330 |
Hazard Classifications【危险分类】 | Acute Tox. 4 Oral |
Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |
WGK | WGK 3 |