您的位置：首页 > 产品中心 > 168021-79-2， HPN-07
HPN-07
产品价格查看更多规格...
| 产品编号 | 包装单位 | 单价(元) | 国内现货 | 国外库存 | 询价单 |
| 4086173 | 5 MG | 1180 | |||
| 4086173 | 25 MG | 4350 |
产品别名
168021-79-2
HPN-07
2, 4-Disulfonyl PBN
NXY-059
Oklahoma nitrone-007
Nxy 059
OKN-007
OKN007
Disufenton sodium
2,4-Disulfophenyl-N-tert-butylnitrone
CPI 22
Disodium 4-[(tert-butyl-imino) methyl]benzene-13-disulfonate N-oxide
ARL 16556
Cerovive
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 | C11H13NO7S2 · 2Na |
| Molecular weight | 381.33 |
| MDL number | MFCD09833648 |
| Biochem/physiol Actions【生化/生理作用】 | Originally characterized for its NO-mimicking activity in preventing peroxynitrite formation and in vivo neuroprotective efficacy in animal models of cerebral ischemia (100 mg/kg i.v. in rabbits; 30-60 mg/kg plus 30-60 mg/kg/h i.v. or 50 mg/kg plus 8.8 mg/kg/h s.c. in rats; 28 mg/kg plus 16 mg/kg/h i.v. in monkeys), OKN-007 (HPN-07, NXY-059) is an orally available α-phenyl-tert-butylnitrone (PBN) derivative that is also shown to exhibit sulfatase 2 (SULF2) inhibitory activity and anticancer efficacy both in cultures (effective conc. 170-200 μM in Huh7 heptoma cultures) and in several rodent glioma models in vivo (C6, RG2, and GL261; 75 mg/kg/day for rats and 168 mg/kg/day for mice via drinking water). |
产品性质
| Assay【测定】 | ≥98% (HPLC) |
| form【形式】 | powder |
| color【颜色】 | white to beige |
| solubility【溶解性】 | H2O: 2 mg/mL, clear |
| storage temp.【储存温度】 | −20℃ |
| SMILES string | [O-]/[N+](C(C)(C)C)=C\C(C=CC(S([O-])(=O)=O)=C1)=C1S([O-])(=O)=O.[Na+].[Na+] |
| InChI | 1S/C11H15NO7S2.2Na/c1-11(2,3)12(13)7-8-4-5-9(20(14,15)16)6-10(8)21(17,18)19;;/h4-7H,1-3H3,(H,14,15,16)(H,17,18,19);;/q;2*+1/p-2 |
| InChI key | XLZOVRYBVCMCGL-UHFFFAOYSA-L |
安全信息
| Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
