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ITE
产品价格查看更多规格...
| 产品编号 | 包装单位 | 单价(元) | 国内现货 | 国外库存 | 询价单 |
| 4086195 | 5 MG | 897 | |||
| 4086195 | 25 MG | 3150 |
产品别名
448906-42-1
ITE
2-(1H-Indole-3-carbonyl)thiazole--4--carboxylic acid methyl ester
Methyl 2-(1H-indole-3-carbonyl)thiazole-4-carboxylate
2-(1′H-Indole-3′-carbonyl)thiazole-4-carboxylic acid methyl ester
2-(1’H-Indole-3′-carbonyl)-thiazole-4-carboxylic acid
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 | C14H10N2O3S |
| Molecular weight | 286.31 |
| MDL number | MFCD06411597 |
| Biochem/physiol Actions【生化/生理作用】 | ITE is an endogenous aryl hydrocarbon (Ah) receptor (AhR) agonist with broad-spectrum species reactivity and 5-fold higher potency than beta-naphthoflavone (by cell-based reporter assay). ITE upregulates CYP1A1/downregulates AhR in Hepa cells (0.1-5 μM), and induces fetus AhR activation in pregnant mice in vivo (1.4mg ITE/mL DMSO/kg bw i.v. on gestation day/GD 14, fetal AhR activation assessed on GD15). Endogenous ligand identified for aryl hydrocarbon receptor (AHR); ligand inducible transcription factor. |
产品性质
| Quality Level【质量水平】 | 100 |
| Assay【测定】 | ≥98% (HPLC) |
| form【形式】 | powder |
| color【颜色】 | white to beige |
| solubility【溶解性】 | DMSO: 2 mg/mL, clear |
| storage temp.【储存温度】 | 2-8℃ |
| SMILES string | COC(=O)c1csc(n1)C(=O)c2c[nH]c3ccccc23 |
安全信息
| Pictograms【象形图】 | GHS07 |
| Signal word【警示用语：】 | Warning |
| Hazard Statements | H315 - H319 - H335 |
| Precautionary Statements | P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338 |
| Hazard Classifications【危险分类】 | Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3 |
| Target Organs【靶器官】 | Respiratory system |
| Storage Class Code【储存分类代码】 | 11 - Combustible Solids |
| WGK | WGK 3 |
