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JI130
产品别名
2234271-86-2
JI130
(E)-N-(2-(Allyloxy)phenethyl)-3-(7-methoxy-1H-indol-3-yl)acrylamide
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 | C23H24N2O3 |
| Molecular weight | 376.45 |
| Biochem/physiol Actions【生化/生理作用】 | JI130 is a cell penetrant, potent and selective inhibitor of the helix-loop-helix transcription factor Hes1 that blocks Hes1-mediated transcriptional repression. JI130 potently inhibits pancreatic cancer cell lines proliferation, and shrink tumor in a mice pancreatic tumor xenograft model. |
产品性质
| Assay【测定】 | ≥95% (HPLC) |
| form【形式】 | powder |
| color【颜色】 | white to beige |
| solubility【溶解性】 | DMSO: 2 mg/mL, clear |
| storage temp.【储存温度】 | 2-8℃ |
| SMILES string | O=C(/C=C/C1=CNC2=C1C=CC=C2OC)NCCC3=CC=CC=C3OCC=C |
安全信息
| Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
