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N6-(4-Hydroxybenzyl) adenine riboside

产品编号:4086262
规格:≥98% (HPLC)
CAS NO:110505-75-4
包装规格:5 MG
产品类别:进口试剂
品牌:Sigma-Aldrich
优惠价:立即咨询
产品编号包装单位单价(元)国内现货国外库存询价单
40862625 MG1450
产品别名

110505-75-4

N6-(4-Hydroxybenzyl) adenine riboside

NHBA

N6-(4-Hydroxybenzyl)-adenosine

N-[(4-Hydroxyphenyl)methyl]adenosine

T1-11

结构式
基本信息
Empirical Formula【经验(实验)分子式】
C17H19N5O5
Molecular weight
373.36
MDL number
MFCD18641957
NACRES
NA.77
Biochem/physiol Actions【生化/生理作用】
N6-(4-Hydroxybenzyl) adenine riboside (NHBA) is an orally available and brain penetrant active active ingredient of Gastrodia elata rhizomes used for the treatment of insomnia. N6-(4-Hydroxybenzyl) adenine riboside is an adenosine A2A receptor and the equilibrative nucleoside transporter 1 (ENT1) agonist. It exhibits sedative and hypnotic effects by binding to adenosine A1 and A2A receptors in mice. N6-(4-Hydroxybenzyl) adenine riboside exerted a therapeutic effect on HD transgenic mouse by decreasing protein level of polyglutamine-expanded huntingtin in the striatum.
产品性质
Quality Level【质量水平】
100
Assay【测定】
≥98% (HPLC)
form【形式】
powder
color【颜色】
white to beige
solubility【溶解性】
DMSO: 2 mg/mL, clear
storage temp.【储存温度】
2-8℃
SMILES string
OC[C@H]1O[C@@H](N2C=NC3=C2N=CN=C3NCC4=CC=C(O)C=C4)[C@H](O)[C@@H]1O
安全信息
Storage Class Code【储存分类代码】
13 - Non Combustible Solids
WGK
WGK 3
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