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NVP-ADW742
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产品编号 | 包装单位 | 单价(元) | 国内现货 | 国外库存 | 询价单 |
4086286 | 5 MG | 1530 | |||
4086286 | 25 MG | 4490 |
产品别名
475488-23-4
NVP-ADW742
5-[3-(Phenylmethoxy)phenyl]-7-[trans-3-(1-pyrrolidinylmethyl)cyclobutyl]-7H-pyrrolo[2,3-d]pyrimidin-4-amine
NVP-ADW 742
基本信息
Empirical Formula【经验(实验)分子式】 | C28H31N5O |
Molecular weight | 453.58 |
NACRES | NA.77 |
Application【应用】 | NVP-ADW742 has been used as an insulin-like growth factor 1 receptor (IGF1R) inhibitor to test the effects of filamin A (FLNA) silencing in a cell proliferation assay. |
Biochem/physiol Actions【生化/生理作用】 | NVP-ADW742 is a potent and selective ATP-competitive inhibitor of Insulin-like growth factor-I receptor (IGF-IR) kinase. NVP-ADW742 sensitizes cancer cell lines to multiple anticancer agents including etoposide, carboplatin, imatinib, vincristine, and doxorubicin. |
产品性质
Quality Level【质量水平】 | 100 |
Assay【测定】 | ≥98% (HPLC) |
form【形式】 | powder |
color【颜色】 | white to beige |
solubility【溶解性】 | DMSO: 2 mg/mL, clear |
storage temp.【储存温度】 | 2-8℃ |
安全信息
Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |
WGK | WGK 3 |