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OLT1177
产品价格查看更多规格...
| 产品编号 | 包装单位 | 单价(元) | 国内现货 | 国外库存 | 询价单 |
| 4086293 | 5 MG | 1096 | |||
| 4086293 | 25 MG | 3850 |
产品别名
54863-37-5
OLT1177
3-(Methylsulfonyl)propanenitrile; 3-(Methylsulfonyl)propionitrile
OLT 1177
Dapansutrile
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 | C4H7NO2S |
| Molecular weight | 133.17 |
| MDL number | MFCD11934305 |
| Biochem/physiol Actions【生化/生理作用】 | OLT1177 is an orally active, specific and potent inhibitor of NLRP3 inflammasome activation that decreases IL-1β and IL-18 release. OLT1177 exhibits no effect on NLRC4 and AIM2 inflammasomes activation. It appears that OLT1177 directly interact with NLRP3. It does not show hematological, or organ toxicities in humans at oral doses up to 1,000 mg/day |
产品性质
| Quality Level【质量水平】 | 100 |
| Assay【测定】 | ≥98% (HPLC) |
| form【形式】 | powder |
| color【颜色】 | white to beige |
| solubility【溶解性】 | DMSO: 2 mg/mL, clear |
| storage temp.【储存温度】 | −20℃ |
| SMILES string | O=S(C)(CCC#N)=O |
安全信息
| Storage Class Code【储存分类代码】 | 11 - Combustible Solids |
| WGK | WGK 3 |
