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PH-797804
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产品编号 | 包装单位 | 单价(元) | 国内现货 | 国外库存 | 询价单 |
4086325 | 5 MG | 1220 | |||
4086325 | 25 MG | 4490 |
产品别名
586379-66-0
PH-797804
3-[3-Bromo-4-[(2,4-difluorophenyl)methoxy]-6-methyl-2-oxo-1(2H)-pyridinyl]-N,4-dimethyl-benzamide
3-Bromo-4-[(2,4-difluorobenzyl)oxy]-1-[5-[(methylamino)carbonyl]-2-methylphenyl]-6-methylpyridin-2(1H)-one
PH 797804
结构式
基本信息
Empirical Formula【经验(实验)分子式】 | C22H19BrF2N2O3 |
Molecular weight | 477.30 |
MDL number | MFCD18251426 |
PubChem Substance ID【PubChem化学物质编号】 | 329823795 |
Biochem/physiol Actions【生化/生理作用】 | PH-797804 is an orally active, potent and readily reversible ATP competitive inhibitor of the alpha isoform of human p38 MAP kinase. PH-797804 blocks inflammation-induced production of cytokines and proinflammatory mediators. |
Other Notes【其他说明】 | This compound was developed by Pfizer for Kinase Phosphatase Biology research. To learn more about Sigma′s partnership with Pfizer and view other authentic, high-quality Pfizer compounds, visit sigma.com/bsm-pfizer. |
Legal Information【法律信息】 | Sold for research purposes under agreement from Pfizer Inc. Pfizer is a registered trademark of Pfizer, Inc. |
产品性质
Quality Level【质量水平】 | 100 |
Assay【测定】 | ≥98% (HPLC) |
form【形式】 | powder |
manufacturer/tradename | Pfizer® |
color【颜色】 | white to beige |
solubility【溶解性】 | DMSO: 10 mg/mL, clear |
originator【创始人】 | Pfizer |
storage temp.【储存温度】 | 20-25℃ |
SMILES string | CC1=CC(OCC2=C(F)C=C(F)C=C2)=C(Br)C(N1C3=CC(C(NC)=O)=CC=C3C)=O |
packaging【包装】 | 5, 25 mg in glass bottle |
安全信息
Pictograms【象形图】 | GHS07 |
Signal word【警示用语:】 | Warning |
Hazard Statements | H302 - H315 - H319 - H335 |
Precautionary Statements | P280 - P301 + P312 + P330 - P304 + P340 + P312 - P305 + P351 + P338 - P337 + P313 |
Hazard Classifications【危险分类】 | Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3 |
Target Organs【靶器官】 | Respiratory system |
Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |
WGK | WGK 3 |