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SK609 hydrochloride
产品别名
1092797-77-7
SK609 hydrochloride
4-(2-Chlorophenyl)butan-2-amine hydrochloride
SK609·HCl
ES609
基本信息
| Empirical Formula【经验(实验)分子式】 | C10H14ClN · HCl |
| Molecular weight | 220.14 |
| Biochem/physiol Actions【生化/生理作用】 | SK609 (ES609) is a Dopamine D3 receptor (D3R) selective agonist with a bias towards the G-protein-dependent pathway rather than recruiting β-arrestin-2 and an EC50 value of 113.9 nM for activation of ERK1/2 phosphorylation. SK609 has been shown to reverse akinesia and reduce L-dopa-induced dyskinesia in a hemiparkinsonian rat model of Parkinson′s desease. It does not induce desensitization of D3R. |
产品性质
| Assay【测定】 | ≥98% (HPLC) |
| form【形式】 | powder |
| storage condition【储存条件】 | protect from light under inert gas |
| color【颜色】 | white to beige |
| solubility【溶解性】 | H2O: 2 mg/mL, clear |
| storage temp.【储存温度】 | 2-8℃ |
安全信息
| Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
