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Diasarone-I
产品别名
80423-94-5
Diasarone-I
1,1′-[(1E)-3-Ethyl-2-methyl-1-propene-1,3-diyl]bis[2,4,5-trimethoxybenzene]
Diasarone 1
(E)-3-ethyl-2-methyl-3-(2′′,4′′,5′′-trimethoxy)phenyl-1-(2′,4′,5′-trimethoxy)phenyl-1-propene
NEOLASA-I
Diasarone I
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 | C24H32O6 |
| Molecular weight | 416.51 |
| Biochem/physiol Actions【生化/生理作用】 | The antiviral effect of Diasarone-I includes half maximal effective concentration (EC50) of 4.5 μM and half maximal cytotoxicity concentration (CC50) of >80 μM. Diasarone-I is an antiviral agent isolated form Acorus tatarinowii Schott that potently inhibits dengue viral infection. Diasarone-I is binds to the viral 2′O methyltransferase of nonstructural protein 5 (NS5). It also decreases the DENV2-induced STAT1 phosphorylation and IFN-stimulated genes (ISGs) expression. |
产品性质
| Assay【测定】 | ≥98% (HPLC) |
| form【形式】 | powder |
| color【颜色】 | white to beige |
| solubility【溶解性】 | DMSO: 2 mg/mL, clear |
| storage temp.【储存温度】 | −20℃ |
| SMILES string | C/C(C(CC)C1=CC(OC)=C(OC)C=C1OC)=C\C2=C(OC)C=C(OC)C(OC)=C2 |
安全信息
| Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
