您的位置：首页 > 产品中心 > 356068-97-8， N-Desethyl sunitinib hydrochloride
N-Desethyl sunitinib hydrochloride
产品价格查看更多规格...
| 产品编号 | 包装单位 | 单价(元) | 国内现货 | 国外库存 | 询价单 |
| 4086886 | 5 MG | 1390 | |||
| 4086886 | 25 MG | 5120 |
产品别名
356068-97-8
N-Desethyl sunitinib hydrochloride
5-(5-Fluoro-2-oxo-1,2-dihydroindol-(3Z)-ylidenemethyl)-2,4-dimethyl-1H-pyrrole-3-carboxylic acid (2-ethylaminoethyl)amide hydrochloride
SU 12662 hydrochloride
SU12662 hydrochloride
N-Desethylsunitinib hydrochloride
N-[2-(Ethylamino)ethyl]-5-[(Z)-(5-fluoro-1,2-dihydro-2-oxo-3H-indol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-carboxamide hydrochloride
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 | C20H23FN4O2 · xHCl |
| Molecular weight | 370.42 (free base basis) |
| MDL number | MFCD18252482 |
| Biochem/physiol Actions【生化/生理作用】 | N-Desethyl sunitinib is a multi-target tyrosine kinase inhibitor that is a major active metabolite of an anticancer drug sunitinib. N-Desethyl sunitinib has a similar kinase inhibitory effect as sunitinib. In patients, plasma sunitinib and N-desethyl sunitinib accounts for 42% and 24%, respectively. Thus N-desethyl sunitinib accounts for one third of the therapeutic effect of oral sunitinib. |
产品性质
| Quality Level【质量水平】 | 100 |
| Assay【测定】 | ≥98% (HPLC) |
| form【形式】 | powder |
| storage condition【储存条件】 | desiccated |
| color【颜色】 | white to beige |
| solubility【溶解性】 | DMSO: 2 mg/mL, clear (warmed) |
| storage temp.【储存温度】 | 2-8℃ |
安全信息
| Pictograms【象形图】 | GHS08,GHS09 |
| Signal word【警示用语：】 | Warning |
| Hazard Statements | H361d - H373 - H410 |
| Precautionary Statements | P202 - P260 - P273 - P280 - P308 + P313 - P391 |
| Hazard Classifications【危险分类】 | Aquatic Acute 1 - Aquatic Chronic 1 - Repr. 2 - STOT RE 2 |
| Storage Class Code【储存分类代码】 | 11 - Combustible Solids |
| WGK | WGK 3 |
