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NAB-14
产品别名
1237541-73-9
NAB-14
N,N-diethyl-, 4-[(1H-indol-7-ylamino)carbonyl]phenyl ester
Carbamic acid
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 | C20H21N3O3 |
| Molecular weight | 351.40 |
| Biochem/physiol Actions【生化/生理作用】 | NAB-14 is a negative allosteric modulator (NAM) selective for GluN2C/2D-containing NMDA glutamate receptors. NAB-14 was >800-fold selective for recombinant GluN2C/GluN2D over GluN2A/GluN2B in Xenopus oocytes and exhibited an IC50 value of 580 nM at recombinant GluN1/GluN2D receptors. |
产品性质
| Assay【测定】 | ≥98% (HPLC) |
| form【形式】 | powder |
| color【颜色】 | white to beige |
| solubility【溶解性】 | DMSO: 2 mg/mL, clear |
| storage temp.【储存温度】 | 2-8℃ |
| SMILES string | CCN(CC)C(OC(C=C1)=CC=C1C(NC2=C3C(C=CN3)=CC=C2)=O)=O |
安全信息
| Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
