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PD166326
产品别名
185039-91-2
PD166326
PD 166326
6-(2,6-Dichlorophenyl)-2-[[3-(hydroxymethyl)phenyl]amino]-8-methyl-pyrido[2,3-d]pyrimidin-7(8H)-one
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 | C21H16Cl2N4O2 |
| Molecular weight | 427.28 |
| NACRES | NA.77 |
| Biochem/physiol Actions【生化/生理作用】 | ATP-competitive dual BCR-ABL and Src kinase inhibitor PD166326 is an ATP-competitive dual BCR-ABL and Src kinase inhibitor. In some studies it has been found to be more potent than imatinib with inhibition of cancer growth in the low nanomolar range or even picomolar range in various biological systems. |
| Legal Information【法律信息】 | Pfizer is a registered trademark of Pfizer, Inc. |
产品性质
| Quality Level【质量水平】 | 100 |
| Assay【测定】 | ≥98% (HPLC) |
| form【形式】 | powder |
| manufacturer/tradename | Pfizer® |
| color【颜色】 | white to light brown |
| solubility【溶解性】 | DMSO: 2 mg/mL, clear |
| originator【创始人】 | Pfizer |
| storage temp.【储存温度】 | room temp |
| SMILES string | O=C1N(C)C2=C(C=NC(NC3=CC=CC(CO)=C3)=N2)C=C1C4=C(Cl)C=CC=C4Cl |
安全信息
| Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
