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Anti-Apobec1 Antibody
| 产品编号： | 4087396 |
| 规格： | from rabbit, purified by affinity chromatography |
| 包装规格： | 100 μG |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品别名
Anti-Apobec1 Antibody
C->U-editing enzyme APOBEC-1, Apolipoprotein B mRNA-editing enzyme 1, HEPR
基本信息
| eCl@ss | 32160702 |
| NACRES | NA.41 |
| General description【一般描述】 | Apolipoprotein B mRNA-editing enzyme 1 (Apobec1) is also known as C->U-editing enzyme APOBEC-1, and HEPR. Apobec1 is a member of the cytidine and deoxycytidylate deaminase family that is exclusively expressed in the small intestine. Apobec1 is a catalytic component of the apolipoprotein B mRNA editing enzyme complex which is responsible for postranscriptional mRNA editing. Apobec1 is also thought to be involved in the epigenetic regulation of gene expression by participating in DNA demethylation. |
| Specificity【特异性】 | Other homologies: Mouse (79% sequence homology). |
| Immunogen【免疫原】 | KLH-conjugated linear peptide corresponding to human Apobec1. |
| Application【应用】 | Research Sub Category Transcription Factors Detect Apobec1 using this rabbit polyclonal antibody, Anti-Apobec1 Antibody validated for use in western blotting & IHC (Paraffin). Research Category Epigenetics & Nuclear Function Immunohistochemistry Analysis: A 1:500-2,000 dilution from a representative lot detected Apobec1 in rat small intestine and human colon tissue. |
| Quality【质量】 | Evaluated by Western Blotting in human spleen tissue lysate. Western Blotting Analysis: 0.1 µg/mL of this antibody detected Apobec1 in 10 µg of human spleen tissue lysate. |
| Physical form【外形】 | Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide. Affinity purified |
| Analysis Note【分析说明】 | Control Human spleen tissue lysate |
| Other Notes【其他说明】 | Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration. |
产品性质
| biological source【生物来源】 | rabbit |
| Quality Level【质量水平】 | 100 |
| antibody form【抗体形式】 | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone【克隆】 | polyclonal |
| purified by【纯化方式】 | affinity chromatography |
| species reactivity | human, rat |
| technique(s) | immunohistochemistry: suitable (paraffin) western blot: suitable |
| NCBI accession no.【NCBI登记号】 | NP_001635 |
| UniProt accession no.【UniProt登记号】 | P41238 |
| shipped in【运输】 | wet ice |
| Gene Information | human ... APOBEC1(339) |
产品说明
| Target description【目标描述】 | ~28 kDa observed |
| Storage and Stability【储存及稳定性】 | Stable for 1 year at 2-8°C from date of receipt. |
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | WGK 1 |
