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Anti-ARMS2 Antibody
| 产品编号： | 4087398 |
| 规格： | from rabbit, purified by affinity chromatography |
| 包装规格： | 100 μG |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品别名
Anti-ARMS2 Antibody
Age-related maculopathy susceptibility protein 2
基本信息
| eCl@ss | 32160702 |
| NACRES | NA.41 |
| General description【一般描述】 | Age-related maculopathy susceptibility protein 2 (ARMS2) is highly expressed in the human placenta and retina. The biological function of ARMS2 has not been fully characterized. However, previous studies have linked mutations in the ARMS2 and HtrA1 genes, located on chromosome 10q26, to the occurrence of age-related macular degeneration type 8, a condition of irreversible vision loss in the elderly. |
| Immunogen【免疫原】 | KLH-conjugated linear peptide corresponding to human ARMS2. |
| Application【应用】 | This Anti-ARMS2 Antibody is validated for use in Western Blotting for the detection of ARMS2. Research Category Neuroscience Research Sub Category Neurodegenerative Diseases Immunocytochemistry Analysis: A representative lot was used by an independent laboratory in ARPE-19 cells. (Pericak-Vance, M., et al. (2009). Invest Ophthalmol Vis Sci. 50(7): 3084–3090.) |
| Quality【质量】 | Evaluated by Western Blot in human placenta tissue lysate. Western Blot Analysis: 1 µg/mL of this antibody detected ARMS2 on 10 µg of human placenta tissue lysate. |
| Physical form【外形】 | Purified rabbit polyclonal in PBS containing 0.1% azide. Affinity purified |
| Analysis Note【分析说明】 | Control Human placenta tissue lysate |
| Other Notes【其他说明】 | Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration. |
产品性质
| biological source【生物来源】 | rabbit |
| Quality Level【质量水平】 | 100 |
| antibody form【抗体形式】 | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone【克隆】 | polyclonal |
| purified by【纯化方式】 | affinity chromatography |
| species reactivity | human |
| technique(s) | western blot: suitable |
| NCBI accession no.【NCBI登记号】 | NP_001093137 |
| UniProt accession no.【UniProt登记号】 | P0C7Q2 |
| shipped in【运输】 | wet ice |
产品说明
| Target description【目标描述】 | ~12 kDa observed. An uncharacterized band appears at ~60 kDa in some lysates. |
| Storage and Stability【储存及稳定性】 | Stable for 1 year at 2-8°C from date of receipt. |
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 10 - Combustible liquids |
