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Anti-Wnt-11 Antibody
产品编号: | 4087514 |
规格: | from rabbit, purified by affinity chromatography |
包装规格: | 100 μG |
产品类别: | 进口试剂 |
品牌: | Sigma-Aldrich |
优惠价: | 立即咨询 |
产品别名
Anti-Wnt-11 Antibody
WNT11
基本信息
eCl@ss | 32160702 |
NACRES | NA.41 |
General description【一般描述】 | Wnt genes belong to a family of protooncogenes with at least 13 known members that are expressed in species ranging from Drosophila to man. Transcription of Wnt family genes appears to be developmentally regulated in a precise temporal and spatial manner. Wnt-11 activity is required for cells to undergo correct convergent extension movements during gastrulation. Wnt-11 is also expressed in the lung mesenchyme, the urorectal septum, the urogenital folds, the labioscrotal swellings, and the cortex of the adrenal gland. Unlike other Wnt family members, Wnt-11 is not expressed in the neuroepithelium of the central nervous system. Wnt-11, along with Wnt-8c, is expressed in the posterior region of the chick embryo in the caudal paraxial mesoderm that underlies the prospective caudal neural plate. |
Immunogen【免疫原】 | KLH-conjugated linear peptide corresponding to the C-terminus of Human Wnt-11. |
Application【应用】 | This Anti-Wnt-11 Antibody is validated for use in Western Blotting for the detection of Wnt-11. |
Quality【质量】 | Evaluated by Western Blot in human osteosarcoma U2OS cell lysate. Western Blot Analysis: 0.5 µg/mL of this antibody detected WNT-11 in 10 µg of human osteosarcoma U2OS cell lysate. |
Other Notes【其他说明】 | Antigen Affinity Purified |
产品性质
biological source【生物来源】 | rabbit |
Quality Level【质量水平】 | 100 |
antibody form【抗体形式】 | affinity isolated antibody |
antibody product type | primary antibodies |
clone【克隆】 | polyclonal |
purified by【纯化方式】 | affinity chromatography |
species reactivity | human |
species reactivity (predicted by homology) | bovine (based on 100% sequence homology), rat (based on 100% sequence homology), rabbit (based on 100% sequence homology), mouse (based on 100% sequence homology) |
technique(s) | western blot: suitable |
NCBI accession no.【NCBI登记号】 | NP_004617 |
UniProt accession no.【UniProt登记号】 | O96014 |
shipped in【运输】 | wet ice |
产品说明
Target description【目标描述】 | ~39 kDa observed |
【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
WGK | WGK 1 |