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产品别名
Anti-MSL3-like 1 Antibody
Male-specific lethal 3 homolog, Male-specific lethal-3 homolog 1, Male-specific lethal-3 protein-like 1, MSL3-like 1
基本信息
| eCl@ss | 32160702 |
| NACRES | NA.41 |
| General description【一般描述】 | MSL3, also known as Male-specific lethal 3 homolog, or Male-specific lethal-3 homolog 1, or Male-specific lethal-3 protein-like 1 (MSL3-like 1), and encoded by the gene MSL3/MSL3L1, is a component of the MSL(male-specific lethal ) histone acetyltransferase complex which is responsible for the majority of histone H4 acetylation at ′Lys-16′ which is implicated in the formation of higher-order chromatin structure. MSL3 may also be involved in chromatin remodeling and transcriptional regulation. Additionally, MSL3 may have a role in X inactivation as its gene is a target for X inactivation. MSL3 is localized to the nucleus. MSL3 is expressed in many tissues including liver, pancreas, heart, lung, kidney, skeletal muscle, brain, and placenta, with highest expression in skeletal muscle and heart. |
| Immunogen【免疫原】 | Linear peptide corresponding to human MSL3-like 1. |
| Application【应用】 | Chromatin Immunoprecipitation Analysis: A representative lot from an independent laboratory immunoprecipitated MSL3-like 1 from HeLa cell lysate (Wu, L., et al. (2011). Mol Cell. 43(1):132-144.). Detect MSL3-like 1 using this Anti-MSL3-like 1 antibody validated for use in western blotting & ChIP. |
| Quality【质量】 | Evaluated by Western Blotting in Jurkat cell lysate. Western Blotting Analysis: 1 µg/mL of this antibody detected MSL3-like 1 in 10 µg of Jurkat cell lysate. |
| Physical form【外形】 | Protein G Purified Format: Purified |
| Other Notes【其他说明】 | Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration. |
产品性质
| biological source【生物来源】 | rabbit |
| Quality Level【质量水平】 | 100 |
| antibody form【抗体形式】 | purified antibody |
| antibody product type | primary antibodies |
| clone【克隆】 | polyclonal |
| species reactivity | human |
| technique(s) | ChIP: suitable western blot: suitable |
| NCBI accession no.【NCBI登记号】 | NP_001180199 |
| UniProt accession no.【UniProt登记号】 | Q8N5Y2 |
| shipped in【运输】 | wet ice |
| Gene Information | human ... MSL3(10943) |
产品说明
| Target description【目标描述】 | ~58 kDa observed. Five isoforms are known to exist at 60 kDa (isoform 1), 53 kDa (isoform 2), 58 kDa (isoform 3), 40 kDa (isoform 4), and 48 kDa (isoform 5). |
| 【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | WGK 1 |
