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Anti-GABAA Receptor (α6 subunit) antibody produced in rabbit
| 产品编号： | 4087574 |
| 规格： | affinity isolated antibody, lyophilized powder |
| 包装规格： | 200 μL |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品别名
Anti-GABAA Receptor (α6 subunit) antibody produced in rabbit
Anti-GABRA6
Anti-γ-Aminobutyric Acid Type A Receptor (α6 subunit)
基本信息
| MDL number | MFCD03845360 |
| NACRES | NA.41 |
| General description【一般描述】 | GABAA and GABAB receptors differ with regard to their ionic characteristics and pharmacological properties. The GABAA receptor is an ionotropic receptor that forms the GABA gated chloride channel and consists of several heterogeneous subunits with membrane recognition sites for benzodiazapenes. |
| Immunogen【免疫原】 | peptide corresponding to amino acids 20-37 of rat GABA(A) α6. This sequence is identical in mouse and shares 17 of 19 residues in human. |
| Application【应用】 | Anti-GABAA Receptor (α 6 subunit) antibody produced in rabbit is suitable for the immunofluorescent detection of GABAA receptor α 6 in cerebella of mice. It is suitable for immunoblotting at a working dilution of 1:200 using rat brain membranes. |
| Biochem/physiol Actions【生化/生理作用】 | The inhibitory neurotransmitter GABA signals through two distinct types of pre- and postsynaptic receptors, GABAA and GABAB. Both GABA receptors can regulate depression of synaptic transmission and be involved in the inhibition controlling neuronal excitability. Mutations in the gene may be responsible for the pathogenesis of childhood absence epilepsy (CAE). Polymorphism in this gene is also related to attenuation in hormonal and blood pressure responses under certain psychological stress. |
| Physical form【外形】 | Lyophilized from phosphate buffered saline, pH 7.4, containing 1% bovine serum albumin, and 0.05% sodium azide. |
产品性质
| biological source【生物来源】 | rabbit |
| Quality Level【质量水平】 | 100 |
| conjugate【偶联物】 | unconjugated |
| antibody form【抗体形式】 | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone【克隆】 | polyclonal |
| form【形式】 | lyophilized powder |
| species reactivity | rat |
| technique(s) | western blot: 1:200 using rat brain membranes |
| UniProt accession no.【UniProt登记号】 | P30191 |
| storage temp.【储存温度】 | −20℃ |
| Gene Information | human ... GABRA6(2559) mouse ... Gabra6(14399) rat ... Gabra6(29708) |
产品说明
| Target description【目标描述】 | Anti-GABA(A) Receptor (α6 subunit) specifically recognizes the GABA(A) receptor α6 subunit protein and may be used for the detection of the GABA(A) receptor α6 subunit protein. The inhibitory neurotransmitter GABA (α-aminobutyricacid |
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 11 - Combustible Solids |
| WGK | WGK 3 |
