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Anti-NOTCH4 (Cleaved-Val1432), C-Terminal antibody produced in rabbit
产品别名
Anti-NOTCH4 (Cleaved-Val1432), C-Terminal antibody produced in rabbit
NOTCH3
notch 4
NOTC4
INT3
neurogenic locus notch 4
基本信息
| NACRES | NA.41 |
| General description【一般描述】 | Anti-NOTCH4 (Cleaved-Val1432) antibody detects endogenous levels of fragment of activated NOTCH4 (Cleaved-Val1432) protein. The NOTCH4 gene is mapped to human chromosome 6p21.32. |
| Immunogen【免疫原】 | The antiserum was produced against synthesized peptide derived from human NOTCH4. Immunogen Range: 1401-1450 |
| Biochem/physiol Actions【生化/生理作用】 | The NOTCH4 gene is associated with the process of angiogenesis and homeostasis during developmental process. NOTCH4 plays a role in Notch signaling pathway which mediates epithelial cell and stem cell homeostasis. Notch signaling pathway is induced in a number of cancer types including colon, breast, pancreatic, cervical, head and neck, renal carcinoma, prostate cancer, Large-cell and Hodgkin lymphomas.Thus, NOTCH4 is known to participate in tumorigenesis. This gene is involved in the development of central nervous system and controls neuronal maturation. Mutations in the gene might be associated with schizophrenia. |
| Features and Benefits【特点和优势】 | Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more. |
| Physical form【外形】 | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
产品性质
| biological source【生物来源】 | rabbit |
| Quality Level【质量水平】 | 100 |
| conjugate【偶联物】 | unconjugated |
| antibody form【抗体形式】 | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone【克隆】 | polyclonal |
| form【形式】 | buffered aqueous solution |
| mol wt【分子量】 | antigen 59 kDa |
| species reactivity | human |
| concentration【浓度】 | ~1 mg/mL |
| technique(s) | ELISA: 1:1000 western blot: 1:500-1:1000 |
| NCBI accession no.【NCBI登记号】 | Q99466 |
| UniProt accession no.【UniProt登记号】 | Q99466 |
| shipped in【运输】 | wet ice |
| storage temp.【储存温度】 | −20℃ |
| Gene Information | human ... NOTCH4(4855) |
产品说明
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | nwg |
