Anti-TREK-1 antibody produced in rabbit

MFCD05865392

NA.41

Potassium two pore domain channel subfamily K member 2 (KCNK2), also known as TWIK-related K⁺ channel-1 (TREK1), is expressed in the spinal cord, bladder and dorsal root ganglion. It is part of the TREK family.

The antibody reacts with rat TREK-1 (confirmed). It is expected that the antibody will also react with human and mouse TREK-1 due to sequence homology (17/18).

synthetic peptide (DPKSA AQNSK PRLSF STKC) corresponding to the intracellular, amino terminus of human TREK-1 (amino acid residues 8-28).

Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.
Western Blotting (1 paper)
Anti-TREK-1 antibody produced in rabbit has been used in western blotting.

Potassium two pore domain channel subfamily K member 2 (KCNK2) possesses a potassium channel activity. It has a role in stabilizing the resting membrane potential of cells. The protein is also involved in the development of rat heart. TREK-1 could act as a drug target to treat acute heart ischemia.

Lyophilized from phosphate buffered saline, pH 7.4, containing 1% bovine serum albumin and 0.025% sodium azide.

rabbit

100

unconjugated

affinity isolated antibody

primary antibodies

polyclonal

buffered aqueous solution

rat

western blot (chemiluminescent): 1:200 using rat brain membranes

Q920B6

−20℃

human ... KCNK2(3776)
rat ... Kcnk2(170899)

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12 - Non Combustible Liquids

WGK 2