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Anti-Puma BH3 domain Antibody
产品别名
Anti-Puma BH3 domain Antibody
BCL2 binding component 3, Bcl-2 binding component 3, p53 up-regulated modulator of apoptosis
基本信息
| eCl@ss | 32160702 |
| NACRES | NA.41 |
| General description【一般描述】 | PUMA is one of the pro-apoptotic Bcl-2 family members including Bax and Noxa, which are also transcriptional targets of p53. The PUMA gene encodes two BH3 domain-containing proteins termed PUMA-a and PUMA-b. PUMA proteins bind Bcl-2, localize to the mitochondria, and induce cytochrome c release and apoptosis in response to p53. PUMA may be a direct mediator of p53-induced apoptosis |
| Specificity【特异性】 | Other species have not been tested. The antibody reacts with the 21 kDa Puma BH3 domain protein. |
| Immunogen【免疫原】 | This antibody was developed against a synthetic peptide selected from the C-terminal region of human Puma. |
| Application【应用】 | Anti-Puma BH3 domain Antibody is an antibody against Puma BH3 domain for use in WB. |
| Quality【质量】 | Western Blot Analysis: 1:250 dilution of this antibody detected Puma BH3 domain on mouse brain lysate. |
| Physical form【外形】 | Protein G Purified Format: Purified |
| Analysis Note【分析说明】 | Control Western Blot : Mouse brain lysate |
| Other Notes【其他说明】 | Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration. |
产品性质
| biological source【生物来源】 | rabbit |
| Quality Level【质量水平】 | 100 |
| antibody form【抗体形式】 | purified antibody |
| antibody product type | primary antibodies |
| clone【克隆】 | polyclonal |
| species reactivity | mouse |
| technique(s) | western blot: suitable |
| NCBI accession no.【NCBI登记号】 | NP_055232 |
| UniProt accession no.【UniProt登记号】 | Q9BXH1 |
| shipped in【运输】 | wet ice |
产品说明
| Target description【目标描述】 | 21 kDa |
| 【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 10 - Combustible liquids |
| WGK | WGK 2 |
