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Anti-Drebrin A/E Antibody
| 产品编号： | 4087904 |
| 规格： | from rabbit, purified by affinity chromatography |
| 包装规格： | 100 μG |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品别名
Anti-Drebrin A/E Antibody
Developmentally-regulated brain protein, drebrin 1, drebrin E, drebrin E2
基本信息
| eCl@ss | 32160702 |
| NACRES | NA.41 |
| General description【一般描述】 | The developmentally-regulated neuron-specific protein, Drebrin A, is expressed first at the time of outgrowth and maturation of dendrites, and is localized within dendrites of the adult brain. Drebrin E+A- signals have been observed in the cell bodies of migrating neuroblasts in the core region; however, only fibrous and punctate drebrin E+A- signals were observed in postmigratory neuroblasts at the outer layers. Studies have demonstrated that the disappearance of drebrin E+A- signals from the cell body coincides with the cessation of neuronal migration. The disappearance of drebrin E from the cell body may be a molecular switch for the cessation of migration in newly generated neuroblast |
| Specificity【特异性】 | May react with human based on sequence homology. Reactivity with other species has not been determined. Cat. # AB10140 detects the internal domain of Drebrin A/E. |
| Immunogen【免疫原】 | KLH conjugated synthetic linear peptide. Epitope: Internal Domain |
| Application【应用】 | Research Sub Category Synapse & Synaptic Biology Detect Drebrin A/E using this Anti-Drebrin A/E Antibody validated for use in WB & IC. Research Category Neuroscience Immunocytochemistry: Proven to react with Drebrin A/E in 16 DIV rat cortical neurons. Photo courtesy of Dr. Gang Lui, Drexel University. |
| Quality【质量】 | Western Blot: A 1:5,000 dilution of this antibody was used to detect embryonic rat brain (day 16) tissue lysate. |
| Physical form【外形】 | Purified rabbit polyclonal antibody in PBS with 0.05% NaN3. Antigen Affinity Purified |
| Analysis Note【分析说明】 | Control Embryonic rat brain (day 16) tissue lysate. |
| Other Notes【其他说明】 | Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration. |
产品性质
| biological source【生物来源】 | rabbit |
| Quality Level【质量水平】 | 100 |
| antibody form【抗体形式】 | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone【克隆】 | polyclonal |
| purified by【纯化方式】 | affinity chromatography |
| species reactivity | mouse, human, rat |
| technique(s) | immunocytochemistry: suitable western blot: suitable |
| NCBI accession no.【NCBI登记号】 | NM_004395.3 |
| UniProt accession no.【UniProt登记号】 | Q07266 |
| shipped in【运输】 | wet ice |
产品说明
| Target description【目标描述】 | ~77 kDa |
| Storage and Stability【储存及稳定性】 | Stable for 1 year at 2-8ºC from date of receipt. |
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 10 - Combustible liquids |
| WGK | WGK 2 |
