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Milli-Mark® Anti-MAPK 1/2 (tERK) Antibody, Alexa Fluor 647 Conjugate
产品别名
Milli-Mark® Anti-MAPK 1/2 (tERK) Antibody, Alexa Fluor 647 Conjugate
Extracellular signal-regulated kinase 1, ERK-1, Insulin-stimulated MAP2 kinase, Mitogen-activated protein kinase 1, MAP kinase 1, MAPK 1, p44-ERK1, ERT2, MAP kinase isoform p44, p44, MAPK, Microtubule-associated protein 2 kinase, MNK1
基本信息
| eCl@ss | 32160702 |
| NACRES | NA.41 |
| General description【一般描述】 | The extracellular signal-regulated kinases 1 and 2 (ERK1 and ERK2), also called MAPK1 and MAPK2, are members of the Mitogen Activated Protein Kinase (MAPK) family of proteins found in all eukaryotes. Because the 44 kDa ERK1 and the 42 kDa ERK2 are highly homologous and both function in the same protein kinase cascade, the two proteins are often referred to collectively as ERK1/2 or MAPK1/2. The MAPK1/2 signaling cascade has been shown to be a critical regulator of cell differentiation, cell physiology and neuronal function. Aberrant control of MAPK1/2 activity has been implicated in a variety of pathological conditions, including cancer and autoimmune diseases, and efficient study methods are in demand. |
| Specificity【特异性】 | Antibody recognizes MAPK1/2. C-terminus. |
| Immunogen【免疫原】 | Epitope: C-terminus KLH-conjugated linear peptide corresponding to rat MAPK 1/2 at the C-terminus. |
| Application【应用】 | Research Sub Category MAP Kinases Milli-Mark Anti-MAPK 1/2 (tERK) Antibody, Alexa Fluor 647 Conjugate detects level of MAPK 1/2 (tERK) & has been published & validated for use in FC. Research Category Signaling |
| Quality【质量】 | Evaluated by flow cytometry using Jurkat cells |
| Physical form【外形】 | Purified rabbit polyclonal antibody conjugated to Alexa Fluor 647 in PBS buffer with 15mg/mL BSA and 0.1% Sodium Azide Protein A purified |
| Analysis Note【分析说明】 | Control Jurkat cells |
| Other Notes【其他说明】 | Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration. |
| Legal Information【法律信息】 | ALEXA FLUOR is a registered trademark of Life Technologies MILLI-MARK is a registered trademark of Merck KGaA, Darmstadt, Germany |
产品性质
| biological source【生物来源】 | rabbit |
| Quality Level【质量水平】 | 100 |
| conjugate【偶联物】 | ALEXA FLUOR® 647 |
| antibody form【抗体形式】 | purified antibody |
| antibody product type | primary antibodies |
| clone【克隆】 | polyclonal |
| species reactivity | human |
| manufacturer/tradename | Milli-Mark® |
| technique(s) | flow cytometry: suitable |
| NCBI accession no.【NCBI登记号】 | NP_059043 |
| UniProt accession no.【UniProt登记号】 | P21708 |
| shipped in【运输】 | wet ice |
产品说明
| Target description【目标描述】 | 43 kDa Calculated |
| Storage and Stability【储存及稳定性】 | Maintained refrigerated at 2-8°C from date of receipt. Protected from light in undiluted aliquots for 6 months from date of receipt. |
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | WGK 2 |
