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Anti-IL-33R ST2 (IL1RL1) Antibody
| 产品编号： | 4088208 |
| 规格： | from rabbit, purified by affinity chromatography |
| 包装规格： | 100 μg |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品别名
Anti-IL-33R ST2 (IL1RL1) Antibody
interleukin 1 receptor-like 1, interleukin-1 receptor-like 1, growth stimulation-expressed, homolog of mouse growth stimulation-expressed, interleukin 1 receptor-related protein, Protein ST23
基本信息
| eCl@ss | 32160702 |
| NACRES | NA.41 |
| General description【一般描述】 | Interleukin-1 receptor-like 1 (IL-33R ST2) is a member of the interleukin-1 receptor family, and is comprised of three Ig-like C2-type domains and a single TIR domain. IL-33R ST2 functions as a receptor for IL-33, and, following phosphorylation with MAPKa/ERK2, MAPK3/ERK1, MAPK8 and/ore MAPK14, serves to recruit IRAK1, IRAk4, MYD88, and TRAF6. It is also thought to have a potential role in the function of helper T-cells. High expression has been reported in colon, kidney, lung, placenta, skeletal muscle, small intestines, and the stomach. Isoform A has been noted to be more prevalent in colon, lung, placenta, testis and stomach, while Isoform B has greater presence in brain, liver and kidney. |
| Specificity【特异性】 | This antibody recognizes the extracellular domain of IL-33R ST2. |
| Immunogen【免疫原】 | Epitope: Extracellular Domain KLH-conjugated linear peptide corresponding to the extracellular domain of human IL-33R ST2. |
| Application【应用】 | Research Sub Category Cytokines & Cytokine Receptors Anti-IL-33R ST2 (IL1RL1) Antibody is an antibody against IL-33R ST2 (IL1RL1) for use in WB, IH(P). Immunohistochemistry Analysis: A 1:300 dilution from a previous lot detected IL-33R ST2 in normal human thymus tissue. Research Category Inflammation & Immunology |
| Quality【质量】 | Evaluated by Western Blot in human kidney tissue lysate. Western Blot Analysis: 0.5 µg/mL of this antibody detected IL-33R ST2 in 10 µg of human kidney tissue lysate. |
| Physical form【外形】 | Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide. Affinity purified |
| Analysis Note【分析说明】 | Control Human kidney tissue lysate |
| Other Notes【其他说明】 | Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration. |
产品性质
| biological source【生物来源】 | rabbit |
| Quality Level【质量水平】 | 100 |
| antibody form【抗体形式】 | affinity isolated antibody |
| clone【克隆】 | polyclonal |
| purified by【纯化方式】 | affinity chromatography |
| species reactivity | human |
| species reactivity (predicted by homology) | chimpanzee (based on 100% sequence homology), primate (based on 100% sequence homology) |
| technique(s) | immunohistochemistry: suitable (paraffin) western blot: suitable |
| NCBI accession no.【NCBI登记号】 | NP_057316 |
| UniProt accession no.【UniProt登记号】 | Q01638 |
| shipped in【运输】 | wet ice |
产品说明
| Target description【目标描述】 | ~30 kDa observed. UniProtKB/Swiss-Prot Q01638 (ILRL1_HUMAN) entry describes 3 isoforms produced by alternative splicing: Isoform A at 63.358 kDa, Isoform B at 36.993 kDa, Isoform C at 29.951 kDa The ~37 kDa product is the secreted form. |
| Storage and Stability【储存及稳定性】 | Stable for 1 year at 2-8°C from date of receipt. |
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | WGK 1 |
